Publications by authors named "Babasoji Percy Omoniwa"
Modulatory properties of Thespesia garckeana (F. Hoffm.) Exell & Hillc. Aqueous fruit extract on female rats reproductive hormones and tissues histology and potential inhibitory activity of its constituents against SRD5α2.
Babasoji Percy Omoniwa Jamiu Oyewole Omirinde Adam Moyosore Afodun Charles Obiora Nwonuma Omolola Soji-Omoniwa
J Ethnopharmacol
December 2023
Article Synopsis
- Thespesia garckeana, known by various names in different regions of Africa, is utilized for its medicinal properties, including as a remedy for female infertility in Nigeria, where its ripe fruit decoction is noted for health benefits.
- The study aimed to evaluate the effects of the aqueous fruit extract of T. garckeana on reproductive tissues and hormones in female rats, while also assessing its potential inhibitory effects on a specific human enzyme (5-alpha reductase 2) using computational methods.
- Twenty-five female rats were divided into five groups to receive different treatments, and after a five-day period, various blood hormones and tissue changes were analyzed to gather insights on the extract's reproductive