Quantifying the effect of inbreeding on average daily gain and Kleiber ratio in Mazandaran native chickens.

The aims of this study was to evaluate inbreeding effects for growth rate (average daily gain from hatch to 8 weeks of age (ADG1-8), average daily gain from hatch to 12 weeks of age (ADG1-12), average daily gain from 8 weeks of age to 12 weeks (ADG8-12), average daily gain from hatch to sex maturity (ADG1-SM), average daily gain from 8 weeks of age to sex maturity (ADG8-SM), average daily gain from 12 weeks to sex maturity (ADG12-SM), and Kleiber ratios (KR1-8, KR1-12, KR8-12) in Mazandaran native chickens. The data set of 82,446 pedigreed individuals over 21 generations was analyzed. All individuals were grouped into three classes based on the inbreeding coefficient: First class contained non-inbred birds (F = 0) and second and third classes contained inbred individuals (0 < F ≤ 5% and F > 5%, respectively).

Endosomal TLR-8 Senses microRNA-1294 Resulting in the Production of NFḱB Dependent Cytokines.

The primary function of toll-like receptor 8 (TLR-8) is the detection of viruses and other microbial pathogens. Recent evidence suggests that TLR-8 also senses host microRNAs (miRNAs) and implicate TLR-8 in autoimmune disorders. This study examined the interaction between miR-1294 and TLR-8.

Early and long-term complications following transanal pull through Soave technique in infants with Hirschsprung's disease.

Background And Aim: Patients undergoing Soave surgery for Hirschsprung's disease are at risk for some complications. The aim of this study was to investigate such short-term and long-term complications and evaluate the outcome of the operation in these patients.

Methods: A case series study was carried out during the last 12 years, during 2007 to 2018 in Besat hospital of Hamadan.

Conservative Management of Postpartum HELLP Syndrome and Intraparenchymal Liver Hematoma; A Case Report.

The HELLP syndrome is an important variant of pre-eclampsia which is known by triad of hemolysis (H), elevated liver enzymes (EL) and low platelet count (LP). Intraparenchymal liver hematoma is a rare and important complication of HELLP syndrome which is a life threatening condition. The incidence of intraparenchymal hematoma of the liver has been reported to vary from 1 in each 40,000 to 250,000 deliveries worldwide.

Early life stress affects mortality rate more than social behavior, gene expression or oxidative damage in honey bee workers.

Early life stressors can affect aging and life expectancy in positive or negative ways. Individuals can adjust their behavior and molecular physiology based on early life experiences but relatively few studies have connected such mechanisms to demographic patterns in social organisms. Sociality buffers individuals from environmental influences and it is unclear how much early life stress affects later life history.