The Effect of Bacterial Composition Shifts in the Oral Microbiota on Alzheimer's Disease.

Alzheimer's disease (AD), a neurological disorder, despite significant advances in medical science, has not yet been definitively cured, and the exact causes of the disease remain unclear. Due to the importance of AD in the clinic, large expenses are spent annually to deal with this neurological disorder, and neurologists warn of an increase in this disease in elderly in the near future. It has been believed that microbiota dysbiosis leads to Alzheimer's as a multi-step disease.

Association of perturbation of oral bacterial with incident of Alzheimer's disease: A pilot study.

Objective: This case-control study was designed to compare the composition of the predominant oral bacterial microbiome in Alzheimer's disease (AD) and control group.

Subject: A total of 30 adult participants (15 AD and 15 healthy individuals) were entered in this study. The composition of oral bacterial microbiome was examined by quantitative real-time polymerase chain reaction (qPCR) using bacterial 16S rDNA gene.

Psychometric Properties of the Persian Version of Dizziness Handicap Inventory.

Introduction: The present study was designed to investigate the psychometric properties of the Persian version of the Dizziness Handicap Inventory (P-DHI). In addition, this research was targeted toward assessing the association of P-DHI with Medical Outcome Study 36-Item Short Form Health Survey (SF-36) and Hospital Anxiety and Depression Scale (HADS). The current study also involved a comparison of the scores of patients and healthy participants and implementation of a factor analysis.

The Onset and Frequency of Spasticity After First Ever Stroke.

Background: Spasticity is one of the most important causes of disability after stroke. In spite of high incidence of spasticity, little is known about the relationship between the occurrence and the development of spasticity. This study aimed to determine risk-factors of post stroke spasticity.

Assessing clogging of laminated hydrophobic membrane during fecal sludge drying.

A new sanitation technology has been proposed in which a laminated hydrophobic membrane contains and enhances drying of fecal sludge in a toilet, with particular focus on application to urban regions of low-income countries. The proposed technology uses a laminated hydrophobic membrane liner as an integral component of container-based sanitation systems. The focus of this study is to quantitatively evaluate the laminate's clogging after repeated use, which will affect replacement interval and might limit the laminate's application in container-based toilets.

Awareness toward stroke in a population-based sample of Iranian adults.

Stroke is the leading cause of death and functional disability. While there have been major advances regarding the management of stroke, a significant proportion of people are still unaware of stroke-related symptoms and risk factors. This study was performed to assess the awareness of stroke's warning signs and risk factors among a sample of Iranian population.

Surgical outcome of foot drop caused by common peroneal nerve injuries; is the glass half full or half empty?

Background: Foot drop is a gait abnormality with various etiologies. The Common Peroneal Nerve (CPN) is one of the most frequently injured peripheral nerves. CPN deficit leads to foot drop.

The relationship between the serum levels of ferritin and the radiological brain injury indices in patients with spontaneous intracerebral hemorrhage.

Objectives: Preclinical studies show that iron plays a key role in mediating neuronal injury. This study was performed in order to identify the relationship between the serum level of ferritin and severity of the brain injury which occur after an Intracerebral hemorrhage (ICH).

Materials And Methods: This was a cross sectional descriptive - analytic study, which was conducted on those patients who had suffered from an ICH and had attended Poursina Hospital.

Predicting in-hospital mortality in Iranian patients with spontaneous intracerebral hemorrhage.

Background: Intracerebral hemorrhage (ICH) is the most fatal subtype of stroke. Despite limited effective therapy, there is no accepted clinical grading scale to predict in-hospital mortality, especially in developing nations. The purpose of this study was to assess the predictors of in-hospital mortality among a sample of Iranian patients with spontaneous ICH for use at the time of the first evaluation.

Iron overload is associated with perihematoma edema growth following intracerebral hemorrhage that may contribute to in-hospital mortality and long-term functional outcome.

Iron overload may contribute to brain damage that involves delayed brain atrophy, edema, and neuronal cell death as well as unfavorable outcome following ischemic stroke and intracerebral hemorrhage (ICH). This prospective study was performed to determine the association of serum ferritin level, an iron storage protein, with perihematoma edema (PHE) growth as well as in-hospital mortality and long-term clinical outcome of patients with ICH. Data was collected from patients with ICH from February 2011 to April 2012.

Prevalence and predictors of depression in Iranian patients with multiple sclerosis: a population-based study.

Depression is a frequent symptom in multiple sclerosis (MS) which has a negative impact on quality of life and cognitive status. The purpose of this study was to determine the prevalence and associated factors of depression, and status of antidepressant use in Iranian MS patients. One-hundred and sixty patients with definite MS were included.

Is serum vitamin D levels associated with disability in patients with newly diagnosed multiple sclerosis?

Background: Although the precise etiology of multiple sclerosis (MS) is unknown, it seems that both genetic and environmental factors are important. Recent studies suggest that low serum vitamin D levels are important environmental factor in MS. The aim of this study was to compare the serum levels of vitamin D between MS patients and healthy subjects, and to determine its association with disability in MS patients.

Epidemiology and clinical characteristics of chronic daily headache in a clinic-based cohort of Iranian population.

Although CDH is a major health care problem encountered in headache clinics, our knowledge about the epidemiological features of CDH is limited in developing countries. The objective of this study was to survey the frequency and clinical features of chronic daily headache (CDH) and its subtypes among Iranian population presenting to a referral tertiary Headache clinic in a University Hospital. This cross-sectional survey was carried out between September 2011 and March 2012.

A randomized open-label study of sodium valproate vs sumatriptan and metoclopramide for prolonged migraine headache.

Objective: The objective of this study is to compare the efficacy and tolerability of intravenous valproic acid (iVPA) with intramuscular metoclopramide + subcutaneous (SQ) sumatriptan for prolonged acute migraine.

Background: Intravenous valproic acid has been explored as a possible treatment of acute migraine. Sumatriptan and newer generation triptans are also effective for migraine.