Analysis of a second family with hereditary non-chromaffin paragangliomas locates the underlying gene at the proximal region of chromosome 11q.

The gene for autosomal, dominantly inherited, non-chromaffin paragangliomas has previously been mapped at 11q23-qter by linkage analysis of a single family. In the present study, we have used genetic markers from 11q for the analysis of two distantly related pedigrees with the same disorder. Linkage analysis and haplotyping indicate that the gene underlying the disorder in the present family is located on chromosome 11q proximal to the tyrosinase gene locus (11q14-q21).

[Computer-assisted obstetric data collection and processing--trial with a system solution].

A system is introduced for the registration and utilization of obstetrical dates. It is based on a new birth journal and a file for date collection in agreement to that. With the aid of a bureau computer a short delivery report will be given for the out-patient department of post-clinical medical attendance, as well as a label with the most important obstetrical dates for the postnatal care will be printed.

[Amniotic fluid embolism caused by uterine rupture with severe coagulopathy].

There is reported on a 35 years old woman, who was delivered of her third child. Six days after the expected day of delivery labour was introduced. On the end of the second stage an amniotic fluid infusion happened.

[Effect of parity status and age of Libyan mothers on body length and birth weight of newborn infants. A comparative study].

The parity status (p.s.) (1st to greater than or equal to 14th para) of 3,283 mothers, who have been delivered in the Central Hospital of Az Zawiyah/Libya between 1980 to 1983, had as well as to the length (average total increase 1.

[The giant infant (birth weight equal to or greater than 5,000 g) in obstetrical records of the Az Zawiyah/Libya Central Hospital].

291 giant babies with a birth weight over 5000 g (= 0.58 per cent) were registered among 49,976 newborns, delivered in the Central Hospital of Az Zawiyah (Libya) within 9 years. Some etiological factors have been made responsible for the origin of this intrauterine macrosomy.

[Delivery outside the hospital. An 11-year analysis of births at a regional hospital].

Between January 1st, 1970 and December 31st, 1980 17,731 women of the area of the gynaecological hospital of Brandenburg/Havel have been delivered, of it 146 (0.8 per cent) out of clinic. The portion of multi- and pluriparae was nearly 80 per cent.

Familial non-chromaffinic paragangliomas (glomus tumors) : clinical aspects.

The clinical aspects of a study of a large family suffering from glomus tumors are presented. A great deal of fragmentary information is obtained from the literature, but never before has so much information been obtained from one single family. The aim of this study was to screen the individual members of this family by careful history, with special interest taken in symptoms which could be indicative of glomus tumors, and by a physical examination.

Familiar non-chromaffinic paragangliomas (glomus tumors). Clinical and genetic aspects (abridged).

The presence of glomus tumors in a large family was investigated by clinical and angioscintigraphic screening methods. Of 295 members of this family 162 persons participated in the study. A total of 47 tumors of the head and neck region were found in 26 patients.