Enhanced Efficacy of Some Antibiotics in the Presence of Silver Nanoparticles Against Clinical Isolate of Recovered from Cystic Fibrosis Patients.

Introduction: Given the increasing frequency of drug-resistant bacteria and the limited progress in developing new antibiotics, it is necessary to explore new methods of combating microbial infections. Nanoparticles, particularly silver nanoparticles (Ag-NPs), have shown exceptional antibacterial characteristics; however, elevated concentrations of Ag-NPs can produce noticeable levels of toxicity in mammalian cells.

Aim: This study examined the potential synergistic effect of combining a low dosage of Ag-NPs and anti-pseudomonas drugs against (ATCC strain) and eleven clinical isolates from cystic fibrosis patients.

Correction: Spinel cobalt-based binary metal oxides as emerging materials for energy harvesting devices: synthesis, characterization and synchrotron radiation-enabled investigation.

[This corrects the article DOI: 10.1039/D4RA03462G.].

Low-dose zinc oxide nanoparticles trigger the growth and biofilm formation of Pseudomonas aeruginosa: a hormetic response.

Introduction: Hormesis describes an inverse dose-response relationship, whereby a high dose of a toxic compound is inhibitory, and a low dose is stimulatory. This study explores the hormetic response of low concentrations of zinc oxide nanoparticles (ZnO NPs) toward Pseudomonas aeruginosa.

Method: Samples of P.

Spinel cobalt-based binary metal oxides as emerging materials for energy harvesting devices: synthesis, characterization and synchrotron radiation-enabled investigation.

The synthesis and characterization of spinel cobalt-based metal oxides (MCoO) with varying 3d-transition metal ions (Ni, Fe, Cu, and Zn) were explored using a hydrothermal process (140 °C for two hours) to be used as alternative counter electrodes for Pt-free dye-sensitized solar cells (DSSCs). Scanning electron microscopy (SEM) and atomic force microscopy (AFM) revealed distinct morphologies for each metal oxide, such as NiCoO nanosheets, Cu CoO nanoleaves, Fe CoO diamond-like, and Zn CoO hexagonal-like structures. The X-ray diffraction analysis confirmed the cubic spinel structure for the prepared MCoO films.

Anti-Bacterial Activity of Green Synthesised Silver and Zinc Oxide Nanoparticles against .

plays a critical role in the development of acne vulgaris. There has been a rise in the number of patients carrying strains that are resistant to antibiotics. Thus, alternative anti-microbial agents are required.

A novel digitonin/graphene oxide/iron oxide nanocomposite: synthesis, physiochemical characterization and antioxidant activity.

In this work, iron oxide (FeO) magnetic nanoparticles (MNPs) and graphene oxide (GO) nanosheets were prepared via the co-precipitation technique and the Modified Hummer method. FeO MNPs and GO nanosheets were combined to prepare FeO/GO nanocomposite and subsequently conjugated with Digitonin (DIG) in order to obtain a dual-targeted delivery system based on DIG/FeO/GO nanocomposite. SEM images reveal the presence of FeO MNPs at a scale of 100 nm, exhibiting dispersion between the GO nanosheets.

The efficacy of biosynthesized silver nanoparticles against Pseudomonas aeruginosa isolates from cystic fibrosis patients.

The high antibiotic resistance of Pseudomonas aeruginosa (PA) makes it critical to develop alternative antimicrobial agents that are effective and affordable. One of the many applications of silver nanoparticles (Ag NPs) is their use as an antimicrobial agent against bacteria resistant to common antibiotics. The key purpose of this research was to assess the antibacterial and antibiofilm effectiveness of biosynthesized Ag NPs against six biofilm-forming clinically isolated strains of PA and one reference strain (ATCC 27853).

Physicochemical Properties of Organic Molecular Ferroelectric Diisopropylammonium Chloride Thin Films.

We fabricated ferroelectric films of the organic molecular diisopropylammonium chloride (DIPAC) using the dip-coating technique and characterized their properties using various methods. Fourier-transform infrared, scanning electron microscopy, and X-ray diffraction analysis revealed the structural features of the films. We also performed ab-initio calculations to investigate the electronic and polar properties of the DIPAC crystal, which were found to be consistent with the experimental results.

The impact of biosynthesized ZnO nanoparticles from Olea europaea (Common Olive) on Pseudomonas aeruginosa growth and biofilm formation.

There is a limitation in the range of effectual antibiotics due to the Pseudomonas aeruginosa (PA) infection due to its innate antimicrobial resistance. Researchers have therefore been concentrating their efforts to discover advanced and cost effective antibacterial agents among the ever-increasing PA bacterial resistance strains. It has been discovered that various nanoparticles can be employed as antimicrobial agents.

Antibacterial activity of multi-metallic (Ag-Cu-Li) nanorods with different metallic combination ratios against Staphylococcus aureus.

Objective: Because of the need to extensively study the synergistic activity of metallic nanoparticles, this study aimed to evaluate the antibacterial activity of mixed metallic nanoparticles, made by differing the weight mixing ratio. We prepared multi-metallic nanorods (NRs) by chemical reduction method, with different ratio combinations of silver Ag and copper Cu, two main batches of nanorods were produced: bimetallic mix made only of Ag-Cu, and trimetallic mix made of Ag-Cu and lithium Li, AgCu NRs and AgCuLi NRs respectively. NaOH was used in the synthesis for the co-reduction of salt precursors.

Chitosan-ZnO nanocomposite coating for inhibition of Listeria monocytogenes on the surface and within white brined cheese.

Several types of cheeses including white brined cheese have been linked to listeriosis outbreaks worldwide. This study aimed to (i) investigate the in vitro inhibitory activity of zinc oxide (ZnO) nanoparticles (NPs) at concentrations of 0.0125-0.

Preparation and Characterization of Polymer Membranes Impregnated with Carbon Nanotubes for Olive Mill Wastewater.

In this study, polymer membrane(s) impregnated with carbon nanotubes (CNTs) were developed, characterized and evaluated for removing phenolic compounds from olive mill wastewater; thus, protecting the environment and public health. Polyethersulfone/functionalized, multi-walled carbon nanotube (PES/fCNTs) membranes were synthesized via the phase inversion method using PES and acid-treated CNTs. The prepared membranes were then characterized by scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR) and contact angle.

Photocatalytic Degradation of Methylene Blue Using Polymeric Membranes Based on Cellulose Acetate Impregnated with ZnO Nanostructures.

This paper studied the photocatalytic degradation of methylene blue (MB) using polymeric membrane impregnated with ZnO nanostructures under UV-light and sunlight irradiation. ZnO nanoparticles and ZnO nanowires were prepared using the hydrothermal technique. Cellulose acetate polymeric membranes were fabricated by the phase inversion method using dimethylformamide (DMF) as a solvent and ZnO nanostructures.

Antimicrobial activity of chitosan coating containing ZnO nanoparticles against E. coli O157:H7 on the surface of white brined cheese.

White brined cheese may serve as an ideal medium for the growth of foodborne pathogens including E. coli O157:H7. The objectives of this study were i) to evaluate the inhibitory effects of zinc oxide (ZnO) nanoparticles against E.

Development, In Vitro Characterization, and In Vivo Toxicity Evaluation of Chitosan-Alginate Nanoporous Carriers Loaded with Cisplatin for Lung Cancer Treatment.

Polysaccharide-based aerogels are promising drug carriers. Being nanoporous with a high specific surface area allows their use as a drug vehicle for various delivery routes. Intratracheal and intravenous administration of free cisplatin causes toxicity in the rat liver, lungs, and kidneys.

Protein immobilization on the surface of polydimethylsiloxane and polymethyl methacrylate microfluidic devices.

PDMS and PMMA are two of the most used polymers in the fabrication of lab-on-chip or microfluidic devices. In order to use these polymers in biological applications, it is sometimes essential to be able to bind biomolecules such as proteins and DNA to the surface of these materials. In this work, we have evaluated a number of processes that have been developed to bind protein to PDMS surfaces which include passive adsorption, passive adsorption with glutaraldehyde cross-linking, (3-aminopropyl) triethoxysilane functionalization followed by glutaraldehyde or 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride cross-linkers.

Cerium oxide and iron oxide nanoparticles abolish the antibacterial activity of ciprofloxacin against gram positive and gram negative biofilm bacteria.

Metal oxide nanoparticles have been suggested as good candidates for the development of antibacterial agents. Cerium oxide (CeO2) and iron oxide (Fe2O3) nanoparticles have been utilized in a number of biomedical applications. Here, the antibacterial activity of CeO2 and Fe2O3 nanoparticles were evaluated on a panel of gram positive and gram negative bacteria in both the planktonic and biofilm cultures.

Magnetic nanoparticles: surface effects and properties related to biomedicine applications.

Due to finite size effects, such as the high surface-to-volume ratio and different crystal structures, magnetic nanoparticles are found to exhibit interesting and considerably different magnetic properties than those found in their corresponding bulk materials. These nanoparticles can be synthesized in several ways (e.g.

Magnetic nanoparticles sensitize MCF-7 breast cancer cells to doxorubicin-induced apoptosis.

Background: Resistance of breast cancer cells to the available chemotherapeutics is a major obstacle to successful treatment. Recent studies have shown that magnetic nanoparticles might have significant application in different medical fields including cancer treatment. The goal of this study is to verify the ability of magnetic nanoparticles to sensitize cancer cells to the clinically available chemotherapy.

Artificial semi-rigid tissue sensitized with natural pigments: Effect of photon radiations.

Background: A new approach for evaluating the optical penetration depth and testing its validity with Monte Carlo simulations and Kubelka-Munk theory is used for artificial semi-rigid tissue sensitized with natural pigments. Photodynamic therapy is a promising cancer treatment in which a photosensitizing drug concentrates in malignant cells and is activated by visible light at certain wavelength.

Materials And Methods: Cheap artificial semi-rigid tissue incorporated with scattering and absorbing materials along with some other composites comparable to normal human tissue has been performed.