[Diagnosis of cutaneous graft-versus-host disease: pathomorphological aspects].

Objective: To study the differential diagnostic value of histological and immunohistochemical signs in skin biopsy specimens in graft-versus-host disease (GVHD).

Material And Methods: Hematoxylin- and eosin-stained skin biopsy specimens from 50 patients with GVHD and 10 patients with toxicoderma were examined; immunohistochemical reactions using antibodies against CD3, CD20, CD4, CD8, FOXP3, CD56, CD1a, and CD68 were performed. The significance of differences between the groups was estimated using the chi2 and Mann-Whitney tests.

[Nutrition value of tropical and subtropical fruits].

The article is devoted to the study of the chemical composition of tropical and subtropical fruit (avocado, papaya and mango), which are now in great numbers are on the appeared on the Russian market. Due to use technology tropical and subtropical fruits can be implemented in almost all areas and regions of the country. Relatively low cost makes these products quite popular among the people.

[Oxidative and hydrolytic deterioration of palm oil and fat products based on it under various conditions of storage and transportation].

Studies have been conducted on the effect of storage conditions for refined deodorized palm oil on the quality and safety: in containers made of ferrous metals (mild steel) at unregulated temperature, in sealed plastic bags at the temperature -20 degrees C in stainless steel under stratification of nitrogen at the temperature of 40+/-1 degrees C. The choice of the objects of study determined by the normative documents of the Russian Federation governing the transportation and storage of vegetable oils and fat products based on them. All samples of palm oil with peroxide value of 1,0 to 1,5 meq O2/kg indicated the presence of a weak foreign taste, is not peculiar impersonalfat, the samples with peroxide value above 1,5 meq O2/kg were observed pronounced off-flavors and odors characteristic of stale oil.

[Composition and content of biologically active substances in rose hips].

The paper studies the chemical composition of the powders obtained from the pulp with the skins and seeds of fruits of wild rose hips. Research results have shown that the main fraction of the powder is dietary fiber, powder of seeds of insoluble fiber in 1,6 and 2,3 higher than in the powder of the fruit with a thin skin and pulp, respectively. The greatest amount of carbohydrates and protein found in powders and pulp of the fruit with a thin skin, and lipids predominate in the powder from the seeds.

[Influence of different iron compounds on lipid complex of vitamin fortified wheat flour under storage].

Influence of different iron compounds at combined vitamin fortification on hygienic and biochemical properties of freshly grounded first-class wheat flour under storage was studied. It proved, that more intensive oxidative and hydrolytic processes take place in the lipid complex of the flour, fortified with ferrous sulfate heptahydrate.

[Immunomorphological characteristics of pulmonary langerhans cell histiocytosis].

Lung tissue specimens, obtained during lung biopsy or resection, were morphologically and immunohistochemically studied in 27 patients with Langerhans cell (LC) histiocytosis (LCH). The latter was diagnosed on the basis of the expression of CD1a and S-100. Without immunophenotyping, its diagnosis was difficult due to impaired tissue architectonics (sclerosis, bullous transformation) and artifacts that were inevitably present during lung biopsy.

[Some aspects of the modeling balanced fetacidic structure in sprets].

Information about the development of a method of fatty basis of food inverse emulsion (spread) modeling is given in the article. Theoretical substantiation of creation of a balanced fatty product of functional purpose is described in the article. Practical research results of spread fatty basis creation from palm, soya and rape oil are presented.

[Elaboration enrich cereals gruels fast preparation for the students].

Reviews results research on the appraisal actual mode of life and actual nutrition student's in the result established breach consumption organism important food substances - carbo-hydrates, fiber foods, vitamins and mineral substances. Establishment level intellectual, physical loading, bad habits, in the result that at the student's reviews oridin different diseases. Science basis need introduce in the retion student's food substances promoting foudation and preservation health.

[Effect of dietary fibers on preservation of lipid component in flour confectionery].

Deterioration of bisquit keeping quality is usually caused by oxidation processes changing quality of fats in the composition of buisquits. The oxidation processes are characterized by changing of acidity - and peroxide number. Experimentally shown that the adding of dietary fiber to the formula of butter bisquit results in delaying of the fat oxidation process.

[Morphological diagnosis of plasmocytic myeloma in trephine biopsy (histological and immunohistochemical criteria)].

Histopathological features of multiple myeloma are reviewed with particular emphasis on its differential diagnosis with reactive plasmocytosis. An algorithm is proposed for examination of bone marrow trephine biopsy in multiple myeloma. Its prognostic factors are discussed.

[Analysis of fatal outcomes issues of typhus fever].

The nature and frequency of complications in patients with typhus fever are of importance for its outcome. The causes of death were studied in 126 patients who had died from this disease. The immediate causes of death were as follows: infectious-toxic shock (31.

[Comparative characteristics of the antioxidants of plant origin introduced in fat emulsion foods].

One of the methods of increasing the quality of fatty products is including in their composition antioxidants, which provide the time of their conservation and improvement of their biological value. From this point of view calls concern a new drug epigallocatechina gallate. On the basis of these studies the prospects of usage were shown epigallocatechina gallate in fatty products and the paths of further applying in creation of food products.

[Fat and content of yakutan horse fat tissue].

The gas chromatography method the fat acid content of the young Yakut horse meat fat tissue lipids was studied in relation to the age group, various parts of the body and anatomic topographic location of the fat/It was determined that the of sixth-month young horse is the source of the PUFA omega-3 that allows to recommend horse meat as a dietary product for atherosclerosis prevention. By medial chain fat content the lipids of the 6 month young horses are close to the lipids of milk fat.

[Study of fatty acid composition of cell membranes during the use of soya oil in diet therapy of patients with cardiovascular diseases].

Anti-atherogenic diet supplemented with 20 g soy oil has been analyzed in patients with coronary artery disease and high blood pressure. The vegetable PUFA omega-3 and omega-6 from soy oil have been found to change physical, biological and chemical property of membranes; improved clinical condition as well as to modify erythrocyte membrane fatty acid composition.

[Experimental model of generalized herpetic infection in newborns].

Generalized herpetic infection (GI) with a predominant involvement of the brain, eye, liver and spleen, in which cell rhexis and hyperchromatosis and large necrotic foci were observed, has been experimentally reproduced in newborn rabbits. Administration of herpes simplex virus at the dose of 5LD50 resulted in the suppression of immune reactions and animal death 4-5 days later. Dose of 2LD50 resulted in the immune response in the lymphoid organs, but the signs of the disease disappeared 5 days after the injection of the virus.

[Medico-biological substantiation of producing carbohydrate-rich mixtures for the nutrition of highly-trained sportsmen].

Medico-biological requirements for the chemical composition of specialized products (mixtures) with high content of carbohydrates have been considered. The mixtures are intended for creation of energy reserves and acceleration of restoration processes in persons who were subjected to high physical and neuro-emotional stresses. The chemical composition and fatty-acid content of the high-carbohydrate nutritional mixture are presented.

[The diagnosis and treatment of complications in the late periods after operations for Hirschsprung's disease in children].

On the basis of examinations of 15 children the authors consider that recurrent constipation and fecal discharges as complications of a remote postoperative period take place more frequently than incontinence of feces. One of the causes of constipation after radical operation for Hirschsprung's disease may be a long hypoganglionic zone of the distal portion of the colon. To solve the question about reoperation of children with Hirschsprung's disease the complex examination must necessarily include the determination of activity of tissue acetylcholinesterase in colon mucosa biopsies, balloon proctography, sphincterotonometry, endoscopic examination of the colon in addition to irrigography.

[Orthostatic hypotension in primary amyloidosis].

Proceeding from clinicoanatomical observation of a 50-year-old man, the authors discuss the pathogenesis of arterial hypotension developing in generalized amyloidosis with severe affection of the cardiovascular and nervous system, and the adrenal glands.

[Alteration of the biologically active substances of a lipid nature during drying of wheat grain].

The influence exerted by the temperature of the wheat grain heating when it is dried in an "elemental" layeron changes in the content of some biologically active lipid-like substances and of the lipids oxidation products was studied. It was made certain that drying at different temperatures of the grain heating tends to produce material changes in the amount of biologically active substances and the lipids oxidation products. There is observed a drop in the content of carotinoids, phospholipids, of the sum-total and individual forms of tocopherols with simultaneous accumulation of the oxidation products.

[Use of pancreatic lipase for determination of the glyceride composition of rice lipids].

The triglyceride composition of rice lipids was investigated, using methods of thin-layer chromatography, enzymic hydrolysis by pancreatic lipase and gas-liquid chromatography. The major portion of triglycerides were tri- and di-unsaturated glycerides. The content of trisaturated glycerides was not more than 0.

[Fatty acid composition of polar lipid fractions of ripening wheat].

By thin-layer chromatography on silica gel L (Czechoslovakia) monoglycerides, diglycerides, free fatty acids and triglycerides were isolated from free lipids of ripeining wheat. The composition of free fatty acids of these fractions was studied by gas-liquid chromatography. The following fatty acids were identified and quantified: C10:0; C12:0; 14:0; C14:1; X15:0; C16:0; C17:0; C18:1; C18:2; C18:3; C20:09 Linoleic, palmitnic, oleic, stearic and linolenic acids accured in large quantities.