[Prognostic factors for development of peritoneal carcinosis in stomach carcinoma].

Objective: Several adjuvant therapy concepts have been developed to improve the treatment of gastric cancer patients. Dealing with intraperitoneal chemotherapy, it seems to be useful to determine suitable prognostic factors for the occurrence of peritoneal carcinosis, as it is possible to select patients who may profit from this therapy.

Methods: Between June 1975 and December 1999 resection of gastric cancer was performed in 575 patients.

[Jejuno-jejunal invagination after Dennis tube insertion for ileus--a rare complication].

In contrast to childhood intussusception, the clinical signs of intussusception in adults are nonspecific. Generally organic alterations of the small bowel cause intussusception in adults. In this case report on a retrograde jejunojejunal intussusception in a 61-year-old male, following removal of an intraoperatively placed intestinal tube for ileus therapy, the clinical symptoms, diagnostic methods and therapy for intussusception are described.

[Combined pH measurement and multiple impedance variation assessments--validation of a new technique for detection of non-acid reflux in the esophagus].

In 10 patients with gastroesophageal reflux disease, defective lower esophageal sphincter and normal motility pH and impedance were measured parallel over 24 hours. All patients had a reflux score > 40 with a total of 736 reflux episodes registered by the pH metry of which 724 (sensitivity: 98.9%) were recognized by impedancemetry and with additional 292 reflux phases registered at a stomach pH > 4 by the impedancemetry of which none was recognized by the pH metry as a reflux of pH > 7.

[Effect of myocardial viability and coronary revascularization on clinical outcome and prognosis: a follow-up study of 161 patients with coronary heart disease].

One hundred and sixty-one consecutive patients (144 male, 57 +/- 9 years) with stable coronary artery disease underwent nuclear imaging for assessment of myocardial viability using Tc-99m sestamibi single-photon emission computed tomography (SPECT) and F-18 fluoro-deoxy-glucose (FDG) positron emission tomography (PET). 88% had a history of chronic myocardial infarction and all had angiographically proven regional wall motion (RWM) abnormalities in the distribution territory of a stenosed or occluded coronary artery. Patients were followed for 29 +/- 6 (22-44) months with 84/161 patients (52%) receiving elective revascularization by either bypass surgery or angioplasty.

[Diagnosis and treatment of local forms of surgical anaerobic non-clostridial infection].

145 patients with such kind of surgical infection have been taken to clarify the cause of it. Aerobic agents were the cause in 16.6% and anaerobic nonclostridial agents--in 33.

Swallowing disorders. Diagnosis and medical treatment.

In this article, the diagnosis and treatment of gastroesophageal reflux (GER), esophageal primary dysmotilities, and esophageal infections were reviewed. Important systemic diseases, including endocrine, neurologic, and collagen vascular types, that affect the esophagus were discussed. Finally, theoretical mechanisms of aspiration and possible reflex bronchoconstriction secondary to GER have been reviewed.

Down's syndrome and the gastrointestinal tract.

Gastrointestinal (GI) abnormalities are frequent in patients with Down's syndrome. In a 12-year retrospective review, we identified 187 patients with Down's syndrome admitted to the Columbia-Presbyterian Medical Center. Twenty-seven had major GI disorders, the most common being duodenal stenosis (DS, nine), gastroesophageal reflux (GER, five), imperforate anus (five), and Hirschsprung's disease (four).

Medical management of disorders of swallowing.

Disorders of swallowing in a given patient can result from abnormalities of dentition, the oral cavity (mouth and pharynx), the cricopharyngeal muscle, esophageal skeletal (proximal) or smooth (distal) muscle, the lower esophageal sphincter, and the stomach. Recent advances include refinements in esophageal manometric techniques with reclassification of motility disorders; newer drugs to treat gastroesophageal reflux; recognition of more frequent infections of the esophagus in immunosuppressed patients; and adaptation of the use of medications such as nitrates and calcium-channel blockers, which were previously primarily cardiotonic, for investigative treatment of esophageal motility abnormalities.

Esophageal dysfunction in Down's syndrome.

Abnormalities in esophageal function were identified in seven children with Down's syndrome. Three had recurrent episodes of pneumonia from gastroesophageal reflux; two of these and one other patient had esophageal strictures. Two patients with Down's syndrome revealed no evidence of gastroesophageal reflux but did show significant abnormalities in esophageal peristalsis.

Therapy of esophageal stricture: a review of 84 patients.

The course of patients with stricture of the esophagus is variable. Operation is effective, but preoperative trials of dilatation are often inadequate. We reviewed the records of 84 patients with esophageal stricture of various causes of assess efficacy of operative and nonoperative management.

Ultrasonographic scanning of the pancreas. Prospective study of clinical results.

The symptoms of pancreatic cancer are nonspecific and are common in the elderly, who are at risk for pancreatic cancer. Ultrasound is an economic means for screening such individuals. This report describes a prospective study of the efficacy of ultrasound in 83 patients with symptoms of pancreatic cancer.