Background: We aim to investigate the proportion of patients (pts) with long-term cognitive outcomes (CO) of PACC and identify associated features.
Methods: We assessed participants through a neuropsychological assessment. The chi-square test was used for comparisons according with time of NPA (within or beyond 6 months since COVID19) and with previously hospitalization status (hospitalized patients, PH; not hospitalized patients, nPH).
Numerous hydrological applications, such as soil erosion estimation, water resource management, and rain driven damage assessment, demand accurate and reliable rainfall erosivity data. However, the scarcity of gauge rainfall records and the inherent uncertainty in satellite and reanalysis-based rainfall datasets limit rainfall erosivity assessment globally. Here, we present a new global rainfall erosivity dataset (0.
View Article and Find Full Text PDFProblem: Knowledge about physical activity in pregnancy is limited compared to general population and several approaches have been used to evaluate duration and intensity of physical activity during pregnancy.
Background: Although physical activity can contribute to maternal and fetal well-being, more than half of women stopped their physical activity because of pregnancy.
Aim: To evaluate the adherence to physical activity of low-risk pregnant women by adapting an Italian version of the PPAQ.
Objectives: Evaluation of sarcopenia from computed tomography (CT) is often based on measuring skeletal muscle area on a single transverse slice. Automatic segmentation of muscle volume has a lower variance and may be a better proxy for the total muscle volume than single-slice areas. The aim of the study was to determine which abdominal and thoracic anatomical volumes were best at predicting the total muscle volume.
View Article and Find Full Text PDFEur J Obstet Gynecol Reprod Biol
September 2024
To minimize the toxicity and impact of combined antiretroviral therapy (cART) on the lifestyle of people living with Human Immunodeficiency Virus (PLWH), scientific community evaluated the efficacy, safety and sustained virologic response of two drugs antiretroviral regimens, in particular dolutegravir (DTG). The effects of deintensification therapy on inflammatory settings are currently unknown in PLWH. Thus, our study explored the inflammatory state in virologically suppressed HIV individuals between patients in treatment with a DTG-containing dual therapy (2DR) versus triple regimen therapies (3DR).
View Article and Find Full Text PDFPatients with multiple myeloma (MM) have an increased risk of sepsis due to underlying disease- and treatment-related immunosuppression. However, data on sepsis incidence, causative pathogens, and impact on outcomes in newly diagnosed MM (NDMM) are limited. We conducted a retrospective observational study of 92 NDMM patients who developed sepsis between 2022 and 2023 at a tertiary care center in Italy.
View Article and Find Full Text PDFBackground: Multiple sclerosis (MS) is frequently accompanied by comorbid conditions.
Objectives: This study aimed to determine the prevalence of key comorbid conditions in people with multiple sclerosis (pwMS) and assess their impact on quality of life and work-related activities.
Methods: A cross-sectional study involving 755 pwMS from two third-level Italian MS centers was conducted.
Challenges drive the state-of-the-art of automated medical image analysis. The quantity of public training data that they provide can limit the performance of their solutions. Public access to the training methodology for these solutions remains absent.
View Article and Find Full Text PDFLand degradation is a complex socio-environmental threat, which generally occurs as multiple concurrent pathways that remain largely unexplored in Europe. Here we present an unprecedented analysis of land multi-degradation in 40 continental countries, using twelve dataset-based processes that were modelled as land degradation convergence and combination pathways in Europe's agricultural (and arable) environments. Using a Land Multi-degradation Index, we find that up to 27%, 35% and 22% of continental agricultural (~2 million km) and arable (~1.
View Article and Find Full Text PDFObesity and overweight are common and complex conditions influenced by multiple genetic and environmental factors. Several genetic variants located in the genes involved in clock systems and fat taste perception can affect metabolic health. In particular, the polymorphisms in and genes were reported to be significantly related to cardiovascular disease, metabolic syndrome, sleep reduction, and evening preference.
View Article and Find Full Text PDFModeling monthly rainfall erosivity is vital to the optimization of measures to control soil erosion. Rain gauge data combined with satellite observations can aid in enhancing rainfall erosivity estimations. Here, we presented a framework which utilized Geographically Weighted Regression approach to model global monthly rainfall erosivity.
View Article and Find Full Text PDFDeforestation reduces the capacity of the terrestrial biosphere to take up toxic pollutant mercury (Hg) and enhances the release of secondary Hg from soils. The consequences of deforestation for Hg cycling are not currently considered by anthropogenic emission inventories or specifically addressed under the global Minamata Convention on Mercury. Using global Hg modeling constrained by field observations, we estimate that net Hg fluxes to the atmosphere due to deforestation are 217 Mg year (95% confidence interval (CI): 134-1650 Mg year) for 2015, approximately 10% of global primary anthropogenic emissions.
View Article and Find Full Text PDFTo validate the performance of automated Prostate Cancer Molecular Imaging Standardized Evaluation (aPROMISE) in quantifying total prostate disease burden with 18F-DCFPyL PET/CT and to evaluate the interobserver and histopathologic concordance in the establishment of dominant and index tumor. Patients with a recent diagnosis of intermediate/high-risk prostate cancer underwent 18F-DCFPyL-PET/CT for staging purpose. In positive-18F-DCFPyL-PET/CT scans, automated prostate tumor segmentation was performed using aPROMISE software and compared to an in-house semiautomatic-manual guided segmentation procedure.
View Article and Find Full Text PDFFuture phosphorus (P) shortages could seriously affect terrestrial productivity and food security. We investigated the changes in topsoil available P (AP) and total P (TP) in China's forests, grasslands, paddy fields, and upland croplands during the 1980s-2010s based on substantial repeated soil P measurements (63,220 samples in the 1980s, 2000s, and 2010s) and machine learning techniques. Between the 1980s and 2010s, total soil AP stock increased with a small but significant rate of 0.
View Article and Find Full Text PDFBackground: In Italy the incidence of malignant mesothelioma (MM) among women is remarkably high, due to the several contexts in which women had been exposed to asbestos. However, very few studies in literature focus on the inorganic lung content in women. The aim of this retrospective, observational study is to investigate the asbestos lung burden, in terms of concentration, dimensions and type of asbestos, in 42 women who died from MM and had been non-occupationally exposed to asbestos during the activity of the asbestos-cement plant located in Broni (Pavia, Northern Italy) where mainly chrysotile, crocidolite and amosite were used.
View Article and Find Full Text PDFNumerous drivers such as farming practices, erosion, land-use change, and soil biogeochemical background, determine the global spatial distribution of phosphorus (P) in agricultural soils. Here, we revised an approach published earlier (called here GPASOIL-v0), in which several global datasets describing these drivers were combined with a process model for soil P dynamics to reconstruct the past and current distribution of P in cropland and grassland soils. The objective of the present update, called GPASOIL-v1, is to incorporate recent advances in process understanding about soil inorganic P dynamics, in datasets to describe the different drivers, and in regional soil P measurements for benchmarking.
View Article and Find Full Text PDFThe present study aimed to investigate the consequence of resource competition between post-emotional processing and concurrent cognitive tasks. Previous studies have shown that such a resource competition engenders both short-term (e.g.
View Article and Find Full Text PDFObesity and overweight represent a growing health problem worldwide. Genes regulating the intake and metabolism of different nutrients can positively or negatively influence the efficacy of nutritional interventions against obesity and its complications. The aim of this study was to assess changes in anthropometric and clinical parameters and the adherence to a Mediterranean diet (MedDiet) over time in relation to nutrigenetic variants in overweight or obese subjects affected by Type 2 Diabetes (T2D) or dysglycemia, who were included in a nutritional program.
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