Publications by authors named "BIJAOUI G"

Study Question: Are anti-Müllerian hormone (AMH) levels lower in women with endometriosis, notably those with endometriomas (OMAs) and deep infiltrating lesions, compared with controls without endometriosis?

Summary Answer: Endometriosis and OMAs per se do not result in lower AMH levels. AMH levels are decreased in women with previous OMA surgery independently of the presence of current OMAs.

What Is Known Already: The impact of endometriosis and OMAs per se on the ovarian reserve is controversial.

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Article Synopsis
  • The study investigates the relationship between oral contraception (OC) use and different types of endometriosis, analyzing data from over 1,000 women, including both controls and those with diagnosed endometriosis.
  • Results indicate that women who have previously used OC, particularly for severe primary dysmenorrhea, show a higher incidence of endometriosis, especially deep infiltrating endometriosis (DIE).
  • However, current OC users do not have an increased prevalence of endometriosis, suggesting that while past OC use may be linked to later diagnosis, it does not directly increase the risk of developing endometriosis.
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Smoking habits did not influence either the risk of any form of endometriosis (superficial peritoneal endometriosis, ovarian endometriomas, and deep infiltrating endometriosis) and did not correlate with the revised American Fertility Society stages or scores.

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Background: Matrix metalloproteinases (MMPs) may contribute to endometriosis. We tested whether eight functional polymorphisms of these genes could modify the risk of endometriosis.

Methods: In this case-control study, 227 endometriosis and 241 controls were genotyped for MMP1 -1607 1G/2G, MMP2 -1575 G/A (MMP2.

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Objective: To investigate whether the controversy about fluctuations of anti-Müllerian hormone (AMH) levels during the menstrual cycle results from differences between the immunoassays currently available: the Beckman Coulter Immunotech kit (Fullerton, CA) and the Diagnostic Systems Laboratories kit (Webster, TX).

Design: Prospective trial.

Setting: Fertility clinics of two tertiary university hospitals.

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Detection and quantification of Mycoplasma genitalium were evaluated in 83 patients with urethritis (group 1), 60 patients with urethral symptoms but no urethritis (group 2), and 50 asymptomatic men (group 3). Quantification of M. genitalium was carried out using real-time polymerase chain reaction (PCR) analysis of first-pass urine samples.

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  • The study aimed to explore how circumcision and urethritis affect the presence of urethral HPV lesions in HIV-negative men with female partners who have genital HPV.
  • Out of 210 men involved, findings showed no significant difference in overall HPV infection rates between circumcised and uncircumcised individuals; however, circumcision influenced the location of HPV lesions.
  • The study highlighted a higher prevalence of urethritis among uncircumcised men and HPV-infected individuals, with rates varying based on the type of lesions present.
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  • Genital Chlamydia trachomatis is a significant public health issue that can lead to infertility and is often challenging to diagnose due to minimal symptoms and difficulties in testing sperm through traditional methods.
  • New techniques like the polymerase chain reaction (PCR) show promise for more effective detection of the infection in sperm samples compared to cell culture methods.
  • The study found that while PCR and urethral cell culture showed similar prevalence rates, PCR was notably more sensitive for detecting Chlamydia in sperm, suggesting it could eliminate the need for urethral sampling in certain male patients.
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  • The study aimed to evaluate the occurrence of herpes simplex virus (HSV) genital infections in men visiting an HPV screening center and to understand its impact on their female partners.
  • Among 135 men examined, a significant number had HPV lesions, with 15.5% also showing clinical signs of genital herpes; HSV-2 was predominantly found in affected areas and sperm samples.
  • Although a statistical link between HSV and HPV was not established, men with both infections had female partners with a higher incidence of advanced cervical lesions.
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Genital bacterial and viral infections may be responsible of couple infertility and may be potentially oncogenic for genital lesions. Genital bacterial infection is associated with human papillomavirus infection in as much as 48% for men and 64% for women. The bacterias most frequently found are intracellular species (29%) and Gram-negative bacilli (14%).

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