Assessing the diagnostic accuracy of artificial intelligence in post-endovascular aneurysm repair endoleak detection using dual-energy computed tomography angiography.

Purpose: The aim of this study was to evaluate the diagnostic accuracy of an artificial intelligence (AI) tool in detecting endoleaks in patients undergoing endovascular aneurysm repair (EVAR) using dual-energy computed tomography angiography (CTA).

Material And Methods: The study involved 95 patients who underwent EVAR and subsequent CTA follow-up. Dualenergy scans were performed, and images were reconstructed as linearly blended (LB) and 40 keV virtual monoenergetic (VMI) images.

Modeling Exact Frequency-Energy Distribution for Quakes by a Probabilistic Cellular Automaton.

We develop the notion of Random Domino Automaton, a simple probabilistic cellular automaton model for earthquake statistics, in order to provide a mechanistic basis for the interrelation of Gutenberg-Richter law and Omori law with the waiting time distribution for earthquakes. In this work, we provide a general algebraic solution to the inverse problem for the model and apply the proposed procedure to seismic data recorded in the Legnica-Głogów Copper District in Poland, which demonstrate the adequacy of the method. The solution of the inverse problem enables adjustment of the model to localization-dependent seismic properties manifested by deviations from Gutenberg-Richter law.

The influence of contrast enhancement and experience of observers on the assessment of mediastinal lymph nodes in sarcoidosis patients.

Purpose: The aim of this study was to assess the influence of contrast enhancement (CE) and experience of observers on the assessment of chest lymph nodes in patients with sarcoidosis.

Material And Methods: A retrospective analysis of chest lymph nodes on computed tomography (CT) examinations, including CE and non-contrast-enhanced (non-CE) phase, was performed on 40 patients with proven diagnosis of sarcoidosis. Phases were separated, anonymized, and randomized.

Atherosclerosis attacks in patients with psoriasis vulgaris but without a relationship with the severity and course of the disease.

Introduction: In recent years numerous research studies have indicated that chronic inflammation in psoriasis can be associated with an increased risk of developing atherosclerosis.

Aim: The presented study was aimed at demonstrating whether patients suffering from psoriasis vulgaris are at a greater risk of developing atherosclerosis depending on the presence of selected cardiovascular risk factors and the course and severity of the disease.

Material And Methods: Sixty-two patients with diagnosed psoriasis vulgaris and 42 healthy volunteers were included in the study.

Coronary age, based on coronary calcium measurement, is increased in patients with morbid obesity.

Purpose: Obesity is a well-known of risk factor for atherosclerosis. However, recently an "obesity paradox" has been discussed, which is considered as a protective effect of obesity on the development coronary artery disease (CAD). An aim of the study was to investigate the risk of CAD in morbidly obese patients using coronary artery calcium measurement.

Noninvasive evaluation of renal tissue oxygenation with blood oxygen level-dependent magnetic resonance imaging early after transplantation has a limited predictive value for the delayed graft function.

Purpose: The aim of this study was to evaluate the feasibility of renal oxygenation assessment using blood oxygen level-dependent (BOLD) magnetic resonance imaging (MRI) in the early period after kidney transplantation and to estimate its prognostic value for delayed graft function.

Material And Methods: Examinations were performed in 50 subjects: 40 patients within a week after the kidney transplantation and 10 healthy controls, using T2*-weighted sequence. Measurements in transplant patients were correlated to basic laboratory parameters in the early period after transplantation and at follow-up.

Chest adipose tissue distribution in patients with morbid obesity.

Purpose: Obesity is a well-known of risk factor for atherosclerosis and the amount of visceral adipose tissue is considered as an independent predictor of coronary artery disease (CAD). An aim of the study was to investigate the distribution of intrathoracic adipose tissue in morbidly obese patients.

Material And Methods: Fifty-one patients with morbid obesity (BMI ≥ 40 kg/m) and thirty controls were scanned in a coronary calcium scoring protocol.

Imaging in a rare case of neuroendocrine tumour with skin metastases.

Purpose: Disseminated malignancies are a diagnostic and therapeutic challenge that is often encountered in radiology. Finding the primary tumour is crucial for planning proper surgical and oncological treatment. Computed tomography (CT) of the thorax and abdomen is typically the initial examination.

Bi-SOC-states in one-dimensional random cellular automaton.

Two statistically stationary states with power-law scaling of avalanches are found in a simple 1 D cellular automaton. Features of the fixed points, the spiral saddle and the saddle with index 1, are investigated. The migration of states of the automaton between these two self-organized criticality states is demonstrated during evolution of the system in computer simulations.

Contrast-Enhanced Ultrasonography in Crohn's Disease Diagnostics.

The chronic nature of Crohn's disease (CD) implicates necessity of multiple control assessments throughout patient's life. It is accepted that in patients with CD requiring disease monitoring, magnetic resonance enterography (MRE) and computed tomography enterography (CTE) are--apart from endoscopy--imaging studies of first choice. In practice, diagnostic imaging of patients with CD is troublesome, since MRE is an expensive and complicated study, and CTE exposes patients to high doses of ionizing radiation.

Contrast-enhanced Ultrasound for Detection of Crohn's Disease Activity: Systematic Review and Meta-analysis.

Background And Aims: Reports on imaging of active Crohn's disease (aCD) using contrast-enhanced ultrasound (CEUS) are encouraging. However, the statistical power of most published papers is limited due to the small size of the patient groups included. This study was performed to verify the diagnostic value of CEUS in detecting aCD.

Contrast-enhanced ultrasonography for the determination of Crohn's disease activity - preliminary experience.

Background: Contrast-enhanced ultrasound (CEUS) is a recent non-invasive modality, which may partially replace currently used techniques (endoscopy, CT enterography and MR enterography) in the diagnostics and assessment of Crohn's disease (CD). The aim of the study was to analyze early experience in the use of CEUS for the measurement of activity and staging of CD.

Material/methods: Eleven patients previously diagnosed with CD were included in the study.

Utilization of human DC-SIGN and L-SIGN for entry and infection of host cells by the New World arenavirus, Junín virus.

The target cell tropism of enveloped viruses is regulated by interactions between viral proteins and cellular receptors determining susceptibility at a host cell, tissue or species level. However, a number of additional cell-surface moieties can also bind viral envelope glycoproteins and could act as capture receptors, serving as attachment factors to concentrate virus particles on the cell surface, or to disseminate the virus infection to target organs or susceptible cells within the host. Here, we used Junín virus (JUNV) or JUNV glycoprotein complex (GPC)-pseudotyped particles to study their ability to be internalized by the human C-type lectins hDC- or hL-SIGN.

Internalization and fusion mechanism of vesicular stomatitis virus and related rhabdoviruses.

Members of the infect a wide variety of animals and plants, and are the causative agents of many important diseases. Rhabdoviruses enter host cells following internalization into endosomes, with the glycoprotein (G protein) mediating both receptor binding to host cells and fusion with the cellular membrane. The recently solved crystal structure of vesicular stomatitis virus G has allowed considerable insight into the mechanism of rhabdovirus entry, in particular the low pH-dependent conformational changes that lead to fusion activation.

Conserved functions of Ikaros in vertebrate lymphocyte development: genetic evidence for distinct larval and adult phases of T cell development and two lineages of B cells in zebrafish.

Zebrafish has been advocated as an alternative animal model to study lymphocyte development, although the similarities in the genetic requirements of lymphopoiesis between fish and mammals have not yet been investigated. In this study, we examine the role of the transcription factor Ikaros in zebrafish lymphopoiesis. In fish larvae homozygous for an ikaros allele predicted to lack the C-terminal zinc fingers, T lymphopoiesis is absent; the presence of V(H)DmuJmu rearrangements in adolescent fish is delayed in mutants.

Loss of the ecdysteroid-inducible E75A orphan nuclear receptor uncouples molting from metamorphosis in Drosophila.

Isoform-specific null mutations were used to define the functions of three orphan members of the nuclear receptor superfamily, E75A, E75B, and E75C, encoded by the E75 early ecdysteroid-inducible gene. E75B mutants are viable and fertile, while E75C mutants die as adults. In contrast, E75A mutants have a reduced ecdysteroid titer during larval development, resulting in developmental delays, developmental arrests, and molting defects.

Cosmids map two incontinentia pigmenti type 1 (IP1) translocation breakpoints to a 180-kb region within a 1.2-Mb YAC contig.

Incontinentia pigmenti (IP) is an X-linked dominant disorder of neuroectodermal development. Based on the observation of six unrelated females with clinical features of nonfamilial IP with constitutional de novo reciprocal X;autosome translocations, a putative incontinentia pigmenti type 1 locus (IP1; MIM No. 308300) was localized to region Xp11.