Characteristics of patients with somatoform pain disorder.

Background: Patients with somatoform pain experience physical pain that cannot be attributed to any underlying medical or physiological cause, and it is often thought to be related to psychological factors. Health professionals encounter difficulties identifying this specific type of chronic pain, leading to suboptimal treatment strategies. Therefore, we aimed to describe the characteristics of patients with somatoform pain, to support the identification of affected patients.

Developmental beta-cell death orchestrates the islet's inflammatory milieu by regulating immune system crosstalk.

While pancreatic beta-cell proliferation has been extensively studied, the role of cell death during islet development remains incompletely understood. Using a genetic model of caspase inhibition in beta cells coupled with mathematical modeling, we here discover an onset of beta-cell death in juvenile zebrafish, which regulates beta-cell mass. Histologically, this beta-cell death is underestimated due to phagocytosis by resident macrophages.

Correlation of screen exposure to stress, learning, cognitive and language performance in children.

The omnipresence of mobile screens and convenience to operate them has led to increased screen time for young children whereas the sequelae of prolonged exposure are not known yet. 70 refugee children (RG) and 111 children of a clinical comparison group (CG) from a help-seeking population (age: M = 5.10; SD = 1.

Immunoinformatic prediction to identify peptides that bind to CD8+ T-cells as potential vaccine candidates.

Background And Aim: , with its diverse virulence factors and immune response evasion mechanisms, presents a formidable challenge as an opportunistic pathogen. Developing an effective vaccine against has proven elusive despite extensive efforts. Autologous lysate (ASL) treatment has proven effective in triggering an immune response against bovine mastitis.

A practical guide to bioimaging research data management in core facilities.

Bioimage data are generated in diverse research fields throughout the life and biomedical sciences. Its potential for advancing scientific progress via modern, data-driven discovery approaches reaches beyond disciplinary borders. To fully exploit this potential, it is necessary to make bioimaging data, in general, multidimensional microscopy images and image series, FAIR, that is, findable, accessible, interoperable and reusable.

Coming to Terms with Our Racecar Brains: Academic Mothers Experiencing Adult Diagnosis of ADHD.

This collaborative autoethnography explores the experiences of women academics and mothers who received late diagnoses of Attention Deficit Hyperactivity Disorder (ADHD). Due to the historical underdiagnosis of women, little research has focused on this specific demographic. We shed light on how ADHD presents in women, interweaving our stories with extant literature and emphasizing the need to understand this demographic's experiences better.

Young children's development after forced displacement: a systematic review.

Objectives: To examine the impact of displacement experiences on 0- to 6-year-old children's social-emotional and cognitive development, as well as influencing factors on reported outcomes.

Study Design: We systematically searched MEDline, Psyndex, Cochrane Library, Web of Science, Elsevier, TandF, Oxford Journal of Refugee Studies, Journal of Immigrant & Refugee Studies, and Canada's Journal on Refugees for existing literature regarding social-emotional and cognitive outcomes in children directly exposed to forced displacement due to political violence. Results were synthesized in the discussion and displayed using harvest plots.

Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery.

Background: Concerns regarding the safety and availability of transfused donor blood have prompted research into a range of techniques to minimise allogeneic transfusion requirements. Cell salvage (CS) describes the recovery of blood from the surgical field, either during or after surgery, for reinfusion back to the patient.

Objectives: To examine the effectiveness of CS in minimising perioperative allogeneic red blood cell transfusion and on other clinical outcomes in adults undergoing elective or non-urgent surgery.

Exploring Mental Health and Development in Refugee Children Through Systematic Play Assessment.

To evaluate a standardized play observation as a measure of young children's mental health and development in a clinical and refugee population. We conducted individual play observations with 70 refugee children aged 3- to 6-years and compared them to a clinical group of 111 age-matched children regarding their level of play development, social interaction during play, traumatic re-enactments, and emotionless-cold play. Additionally, we assessed children's mental health, social-emotional development and markers of adversity by parent and educator report as well as their IQ-test scores and learning performance and related these factors to the play variables.

Hydrochorous Seed Transport in the Lower Traisen River before and after Riverbed Restoration.

Hydrological restoration was carried out in a Lower Traisen, a small river within the floodplain of the Danube. The main goal was the reestablishment of typical riparian plant communities by using the potential of natural dispersal processes. We studied the transport of plant diaspores in the river water before and after the reconstruction of the riverbed.

Hypertonic Saline Versus Other Intracranial-Pressure-Lowering Agents for Patients with Acute Traumatic Brain Injury: A Systematic Review and Meta-analysis.

Acute traumatic brain injury (TBI) is a major cause of mortality and disability worldwide. Intracranial pressure (ICP)-lowering is a critical management priority in patients with moderate to severe acute TBI. We aimed to evaluate the clinical efficacy and safety of hypertonic saline (HTS) versus other ICP-lowering agents in patients with TBI.

Setting up a data management infrastructure for bioimaging.

While the FAIR (indable, ccessible, nteroperable, and e-usable) principles are well accepted in the scientific community, there are still many challenges in implementing them in the day-to-day scientific process. Data management of microscopy images poses special challenges due to the volume, variety, and many proprietary formats. In particular, appropriate metadata collection, a basic requirement for FAIR data, is a real challenge for scientists due to the technical and content-related aspects.

Genotyping-by-sequencing reveals range expansion of Adonis vernalis (Ranunculaceae) from Southeastern Europe into the zonal Euro-Siberian steppe.

The Euro-Siberian steppe flora consists of warm- and cold-adapted species, which may have responded differently to Pleistocene glacials and interglacials. Genotyping-by-sequencing individuals from across the distribution range of the pheasant's eye (Adonis vernalis), we aimed to gain insight into steppe florogenesis based on the species' evolutionary history. Although the primary area of origin of the species group comprising A.

Markers of inflammation in obese pregnant women: Adenosine deaminase and high sensitive C - reactive protein.

Introduction: The worldwide increase in the prevalence of obesity over the years has emerged as a global health concern. The growing rate of obesity in women of child bearing age is particularly a matter of concern. Obesity is considered a risk factor that predisposes an individual to a proinflammatory state through the release of the inflammatory mediators.

Obstructive Sleep Apnea Among Army Aircrew.

Obstructive sleep apnea (OSA) is a condition characterized by disrupted sleep and excessive daytime fatigue. Associated cognitive and psychomotor decrements pose a threat to aviators' performance and flight safety. Additionally, the longer term health effects associated with the disease can jeopardize an aviator's career and negatively impact operational outputs.

A new approach to manipulating aviator workload: A case for individualizing workload manipulations.

The present study sought to manipulate workload individually for participants to evaluate whether individual manipulations of workload produces similar subjective ratings and performance changes across participants. Participants included eight Army-rated rotary-wing aviators who presented to the laboratory for two separate visits. During the first visit, individual responses to workload were determined, and during the second visit, individually manipulated high workload flights were completed.

Detecting functional deficits following sub-concussive head impacts: the relationship between head impact kinematics and visual-vestibular balance performance.

: Mild traumatic brain injury (mTBI) continues to be a significant issue facing the US military. While TBI cases in deployed environments are of significant concern, an estimated 80% of diagnoses occur in garrison settings (e.g.

Genetic Diversity of L. (Hydrocharitaceae) Stands across Europe.

Intense land use and river regulations have led to the destruction of wetland habitats in the past 150 years. One plant that is affected by the reduction in appropriate habitats is the macrophyte which has become rare in several areas. The preservation of genetic diversity within a species is a prerequisite for survival under changing environmental conditions.

Functional performance differences between carbon fiber and fiberglass prosthetic feet.

Background: Persons with lower limb amputation require increased functionality. The largest category of feet for active individuals with a transtibial amputation is energy storage and return (ESR) feet. These feet are typically constructed of carbon fiber composite materials.

The phylogeographic history of Krascheninnikovia reflects the development of dry steppes and semi-deserts in Eurasia.

Constituting one of Earth's major biomes, steppes are characterised by naturally treeless extra-tropical vegetation. The formation of the Eurasian steppe belt, the largest steppe region in the world, began in Central Asia during the Neogene. In the glacial stages of the Pleistocene, steppe displaced forest vegetation, which in turn recolonised the area during the warmer interglacial periods, thus affecting the distribution of plants adapted to these habitats.

Selective Serotonin Reuptake Inhibitor Use Among Army Aviators.

Mental health is an important aspect of Army aviation medicine given that it significantly impacts career longevity, readiness, and healthcare usage. One of the most commonly used classes of medications to treat mental health disorders is the selective serotonin reuptake inhibitor (SSRI). Here we present a descriptive epidemiological review of SSRI use in Army aviators over a 10-yr period.