[Effectiveness of biological prosthesis for femoro-femoral bypass in high risk patients].

Aim: To compare synthetic and biological prostheses for femoral bypass surgery.

Material And Methods: There were 40 patients with critical ischemia of lower extremities due to atherosclerotic lesion of aorto-iliac segment and severe comorbidities. They were divided into 2 groups by 20 patients.

[Results of administering oral anticoagulants for treatment of patients with venous thromboembolic complications].

The objective of the study was to compare safety and efficacy of rivaroxaban and dabigatran with warfarin in treatment of patients with acute venous thromboembolic complications (VTEC). The authors analysed the results of examining and treating a total of 95 patients presenting with VTEC and randomly divided into three groups. In all groups the initial anticoagulant therapy consisted in unfractionated heparin administered for 5 days, after which the patients followed by switching were switched to a 6-month course of treatment with oral anticoagulants.

[Results of using various methods of autovenous femoropopliteal bypass grafting below the knee-joint fissure].

The objective of the study was to improve therapeutic outcomes in patients presenting with lower limb critical ischaemia by means of optimizing the technique of femoropopliteal bypass grafting. The authors analysed the results of comprehensive examination and treatment of a total of 90 patients presenting with critical lower limb ischaemia on the background of atherosclerotic lesions of arteries of the femoropopliteal and crural segments. Depending on the technology of performing femoropopliteal bypass grafting, the patients were subdivided into three groups each consisting of 30 subjects.

[Free autovenous graft with destructed valves in treatment of severe ischemia of lower extremities].

Aim: to improve treatment of patients with severe atherosclerotic lesion of lower extremities arteries followed by critical ischemia by optimization of femoropopliteal bypass surgery.

Material And Methods: Treament and survey of 60 patients with severe atherosclerotic lesion of femoropopliteotibial segment and critical lower limb ischemia were analyzed. Patients were divided into 2 groups depending on technique of femoropopliteal bypass.

EFFICACY OF FREE AUTOVENOUS TRANSPLANT IN FEMORAL-POPLITEAL BYPASS BELOW THE JOINT SPACE OF THE KNEE.

The article presents an analysis of complex examination and treatment of 60 patients with critical ischemia of the lower extremities due to atherosclerotic lesions of femoral-poplitealtibia segment. Typical traditional autovenous bypass of reverse big saphena was performed for the first (control) group of patients. The operation, which used an original technology by free autovenous transplant with collapsed valves without vein reverse, was completed for the second (experimental) group of patients.

[CHOICE OF PROSTHESIS IN AXILLOFEMORAL BYPASS IN PATIENTS WITH HIGH RISK AND MULTILEVEL LESIONS OF LOWER LIMB ARTERIES].

An analysis of results of experimental research was made in 60 patients with critical ischemia of lower extremities due to bilaterally atherosclerotic lesions of aorto-iliac segment, which had a high operationally anaesthetic risk. Synthetic polytetrafluoethylene prosthesis or biological shunt from internal pectoral bull arteries were used as a shunt. Revasculization was performed through the system of arteria profunda femoris considering multilevel lesions of lower limb arteries.

[Use of a biological graft for subclavian-femoral bypassing in patients at operational-anaesthesiological risk].

Unlabelled: Analysed herein are the results of an experimental study performed on 30 rabbits and a clinical study of treating a total of 60 patients presenting with critical ischaemia of lower limbs on the background of bilateral atherosclerotic lesions of the aortoiliac segment and running high operational-anaesthesiological risk. The animals were subdivided into three groups: an intact group consisting of 6 animals and two study groups comprising 12 rabbits each. In the first study group onto the wall of the abdominal aorta we implanted a synthetic polytetrafluoroethylene prosthesis, the second study group animals received biological graft "Kemangioprotez" from bovine internal thoracic arteries.

[Advantages and disadvantages of warfarin and pradaxa therapy for venous thromboembolism].

An analysis of complex examination of 110 patients with venous thromboembolism was made. The patients were separated into 2 groups. The first group included 60 patients, who had the start heparin therapy during 7 days with the following 6-month warfarin therapy.

[Optimization of anticoagulation therapy for venous thromboembolism].

Objective: To optimize anticoagulation therapy for venous thromboembolism by means of dabigatran etexilate.

Material And Methods: From 2006 to 2012, within the framework of the international trials RE-COVER and RE-COVER II aimed at evaluating efficacy and safety of dabigatran etexilate compared to warfarin, a total of 95 patients meeting the inclusion and exclusion criteria were enrolled in our study. As part of the RE-COVER trial, we carried out analysis of comprehensive examination and treatment of 55 patients with venous thromboembolism (VTE), who were randomly divided into two groups.

[Efficiency of bioprosthesis in case of axillary-femoral bypass in patients with high operative risk].

It was analyzed the treatment results of 60 male patients with critical limb ischemia in case of atherosclerotic lesions of the aorta-iliac segment and severe somatic diseases. All patients were divided into 2 groups. Every group consisted 30 patients.

[State of crural perforating veins after sclerosurgical interventions for lower limb varicose disease].

Analysed herein are the findings obtained by comprehensive examination of 106 patients presenting with grade C3 chronic venous insufficiency according to the CEAP classification. Localization, intensity and extent of refluxes of blood in the venous system of the affected extremity were determined by means of ultrasonographic angioscanning. Based on the obtained results, the patients were subdivided into two groups.

[Choice of the method of minimally invasive treatment of high venovenous blood reflux in patients with varicose disease of the lower extremity veins].

An analysis of complex examination and the following treatment of 337 patients with varicose disease was made. According to the results of the examination three groups of patients were established: the first group--of low intensive, the second group--of mean intensive, the third group--of highly intensive blood reflux. The patients of the first group were treated by the method of injection-sclerosing therapy.

[Sclerotherapy of sapheno-femoral reflux of blood in patients with initial stages of varicose disease of the lower extremity veins].

The results of ultrasonic investigation and the following phlebosclerosing treatment of an incompetent saphenofemoral anastomosis were analyzed in two groups of patients with initial stages of varicose disease of the lower extremity veins. The first group included 48 patients treated by injection-sclerosing therapy by the technology of "empty vein". The second group consisted of 82 patients treated by catheter sclerotherapy of the sapheno-femoral anastomosis.

[Role of blood refluxes in the genesis of venous trophic disorders in patients with chronic venous insufficiency].

The authors analyzed the results of a comprehensive examination of 120 patients with class C6 chronic venous insufficiency according to the CEAP classification, and open trophic ulcers. The patients were subdivided into 2 groups. Group One comprised a total of 75 patients with varicosity, and Group Two consisted of 45 patients with post-thrombotic disease.

[Treatment of critical lower limb ischemia at elderly and old patients with severe concomitant diseases].

Effect of 96% ethanol para-neural injection on sympathetic trunk has been studied experimentally on 18 rabbits. It is demonstrated that ethanol injection leads to dystrophic alteration of sympathetic ganglia and acute aseptic inflammation of para-neural tissues. Clinical study has been carried out on 40 elderly and old patients with critical lower limb ischemia and diffuse arterial occlusive disease.

[Experimental and clinical grounds of revascularizing osteomyoplasty for treatment of critical ischemia of the lower extremities].

In an experimental work it was found that under conditions of muscle ischemia the revascularizing osteomyoplasty was better than revascularizing osteotrepanation: it resulted in 1.4 times greater diameter of muscle fibers and 1.3 times larger size of the capillary network.

[Effects of blood refluxes on formation of trophic ulcers in patients with postthrombotic disease].

The results of complex examination of 45 patients with chronic venous insufficiency having class C6 open trophic ulcers by CEAP classification due to postthrombotic disease were analyzed. The localization, intensity and duration of blood refluxes in the venous system of the injured extremity were determined using ultrasonic angioscanning. Highly intensive total reflux of blood in the popliteal and talocrural segments of the lower extremity venous system found in 68.

[Lumbar chemical sympathectomy in complex treatment of critical impairments of microcirculation in patients with decompensated forms of chronic venous insufficiency].

The authors describe a method of chemical lumbar sympathectomy under USI control in 40 patients. No complications were noted. Positive effect was observed for 2 months.

[Hemodynamic characteristics and surgical treatment of varicose disease with primary involvement of deep vein valves].

Results of clinical examinations and ultrasonic duplex scanning of the venous system of the lower extremities performed in 31 patients with the varicose disease were analyzed. The disease developed due to the primary valve insufficiency of the profound veins. This form is characterized by total-subtotal refluxes of blood along the subcutaneous veins, multiple lesions of the perforant veins, the presence of the hemodynamically valuable blood refluxes in the profound and muscle veins.

[Sclerotherapy of high venovenous blood reflux in patients with early varicose disease of the lower extremities].

Results of diagnosis and treatment of 270 patients with varicose disease were analyzed. Based on duplex scanning two groups of patients were divided: group 1 consisted of 164 patients with low-intensity reflux, group 2 consisted of 106 patients with high-intensity reflux. Patients of group 1 were treated with ultrasound-assisted puncture sclerotherapy.

[Minimally invasive surgery of acute superficial varicothrombophlebitis in patients having somatic contraindication to venectomy].

An analysis was made of complex examination and the following treatment of 21 patients with acute superficial varicothrombophlebitis who had some pronounced pathology of internal organs preventing radical treatment. An original technology of treatment of varicothrombophlebitis developed by the authors includes crossectomy, truncal catheter sclerotherapy up to the place of thrombosis of the subcutaneous veins, stage-wise phlebocentesis of the thrombosed veins followed by injectional sclerotherapy with the ultrasonic control. The thrombophlebitis phenomena were arrested in all patients.

[Optimization of the injection-sclerosing therapy of varicose disease of the lower extremities].

Results of treatment of two groups of patients were analyzed. The first (investigation) group included 106 patients with varicose disease who were given injection-sclerosing therapy by two original methods of elimination of high and low veno-venous refluxes under ultrasound control. The second group consisted of 82 patients treated by traditional methods of sclerotherapy without a purposeful elimination of veno-venous refluxes.

[The mechanisms of the natural history of small pelvis varicosis].

An analysis was made of the results of an all-round clinical, ultrasound, phlebotonometric and phlebographic examination of 89 patients with the clinical evidence of chronic venous insufficiency (CVI) of the pelvis. It is established that small pelvis varicosis develops because of hemodynamic disorders in the system of the inferior vena cava, iliac and left renal veins. In men, blood reflux from the iliac vein to the parietal tributaries leads to the development of the atypical forms of varicosis.

[Sclerotherapy of small pelvis varicosis].

This paper analyses the results of sclerotherapy provided to 89 patients with small pelvis varicosis. Selection of the treatment technology depended on the clinical variant of disease. In patients with damage to the parietal venous system of the pelvis, the treatment was realized by multiple repeat injections of a sclerosing agent to the pelvic veins in a minimal dose which may induce only proliferative processes in varicose vein walls.

[The diagnosis and treatment of chronic venous insufficiency of the pelvis of non-occlusive genesis].

The clinical, ultrasonic duplex scanning and phlebographic (retrograde pelvis renoovaricography) examinations of 89 patients with chronic venous insufficiency of the pelvis were analyzed. Two forms of the clinical course of the disease were established: parietal and visceral. A detailed clinical, ultrasonic and phlebographic characteristics of these forms are described.