Sustainable production of microbial protein from carbon dioxide in the integrated bioelectrochemical system using recycled nitrogen sources.

Given the urgency of climate change, it is imperative to develop innovative technologies for repurposing CO into value-added products to achieve carbon neutrality. Additionally, repurposing nitrogen-source-derived wastewater streams is crucial, focusing on sustainability rather than conventional nitrogen removal in wastewater treatment plants. In this context, microbial protein (MP) production presents a sustainable and promising approach for transforming recovered low-value resources into high-quality feed and food.

Franch. and Sav. Attenuates Respiratory Inflammation Caused by Asian Sand Dust.

Asian sand dust (ASD), generally produced in East Asia, including China, Japan, and Korea, directly leads to the development of pulmonary disease and exacerbates underlying pulmonary diseases. Franch. and Sav.

Biocompatible Cu/NiMo Composite Electrocatalyst for Hydrogen Evolution Reaction in Microbial Electrosynthesis; Unveiling the Self-Detoxification Effect of Cu.

H-driven microbial electrosynthesis (MES) is an emerging bioelectrochemical technology that enables the production of complex compounds from CO. Although the performance of microbial fermentation in the MES system is closely related to the H production rate, high-performing metallic H-evolving catalysts (HEC) generate cytotoxic HO and metal cations from undesirable side reactions, severely damaging microorganisms. Herein, a novel design for self-detoxifying metallic HEC, resulting in biologically benign H production, is reported.

Chondroprotective effects of larvae as an edible insect on osteoarthritis in mice.

Osteoarthritis (OA) is a common chronic joint inflammatory disease characterized by progressive destruction of the articular cartilage, bone remodeling, and excessive chronic pain. Most therapeutic approaches do not rescue the progression of OA effectively or provide relief of symptoms. larva (PBSL), which is attracting attention, is an edible insect with very high nutritional value and herbal medicine for the treatment of blood stasis, hepatic disease, and various inflammatory diseases.

Comparative Morphology of Island and Inland Agastache rugosa and Their Gastroprotective Effects in EtOH/HCl-Induced Gastric Mucosal Gastritis.

Kuntze (Lamiaceae; Labiatae), a medicinal and functional herb used to treat gastrointestinal diseases, grows well both on islands and inland areas in South Korea. Thus, we aimed to reveal the morphological and micromorphological differences between grown on island and inland areas and their pharmacological effects on gastritis in an animal model by combining morphological and mass spectrophotometric analyses. Morphological analysis showed that island had slightly smaller plants and leaves than inland plants; however, the density of all types of trichomes on the leaves, petioles, and stems of island was significantly higher than that of inland plants.

(L.) Kuntze Extract Attenuates Ovalbumin-Induced Allergic Asthma by Regulating Airway Inflammation and Mucus Hypersecretion.

Asthma is a pulmonary disease induced by the inhalation of aeroallergens and subsequent inappropriate immune responses. (L.) Kuntze has been evaluated as an effective antioxidant supplement produced from bioactive compounds, including flavonoids.

Rapid neck elongation in Sauropterygia (Reptilia: Diapsida) revealed by a new basal pachypleurosaur from the Lower Triassic of China.

Neck elongation has appeared independently in several tetrapod groups, including giraffes and sauropod dinosaurs on land, birds and pterosaurs in the air, and sauropterygians (plesiosaurs and relatives) in the oceans. Long necks arose in Early Triassic sauropterygians, but the nature and rate of that elongation has not been documented. Here, we report a new species of pachypleurosaurid sauropterygian, Chusaurus xiangensis gen.

Protective effects of Angelica decursiva Franchet & Savatier on allergic responses through enhancement of Nrf2 and suppression of NF-kB/MMP-9 in ovalbumin-exposed mice.

Ethnopharmacological Relevance: Angelica decursiva Franchet & Savatier is a traditional medicinal plant used to treat asthma, cough, headache, pyrexia and thick phlegm in China, Japan and Korea. A. decursiva contains many types of coumarins, which can exert several pharmacological activities including anti-inflammatory and antioxidant properties for treating various diseases such as pneumonitis, atopic dermatitis, diabetes, and Alzheimer's disease.

New Sesquiterpene Glycosides from the Flowers of and Their Inhibition Activities on EGF- and TPA-Induced Cell Transformation.

In total, four new eudesmane-type sesquiterpene glycosides, askoseosides A-D (-), and 18 known compounds (-) were isolated from the flowers of via chromatographic techniques. Chemical structures of the isolated compounds were identified by spectroscopic/spectrometric methods, including NMR and HRESIMS, and the absolute configuration of the new compounds ( and ) was performed by electronic circular dichroism (ECD) studies. Further, the anticancer activities of the isolated compounds (-) were evaluated using the epidermal growth factor (EGF)-induced as well as the 12--tetradecanoylphorbol 13-acetate (TPA)-induced cell transformation assay.

Chemical Constituents from the Roots of That Improve Glucose-Stimulated Insulin Secretion by Regulating Pancreatic β-Cell Metabolism.

The aim of this study was to discover bioactive constituents of that improve glucose-stimulated insulin secretion (GSIS) in pancreatic β-cells. Herein, three new compounds, namely, koseonolin A (), koseonolin B (), and isohydroxylomatin (), along with 28 compounds (-) were isolated from the roots of . by chromatographic methods.

In vitro propagation of Codonopsis pilosula (Franch.) Nannf. using apical shoot segments and phytochemical assessments of the maternal and regenerated plants.

Background: Codonopsis pilosula (Franch.) Nannf. is a medicinal plant traditionally used in China, Korea, and Japan to treat many diseases including poor gastrointestinal function, low immunity, gastric ulcers, and chronic gastritis.

Effectiveness of Sopoongsan for chronic upper body pruritus in patients with atopic or seborrheic dermatitis: A pilot study protocol for a randomized, double-blind, placebo-controlled, parallel trial.

Introduction: Chronic pruritus persists for > 6 weeks and is known to decrease patients' quality of life. Due to the complex pathological mechanism of chronic pruritus, there is still a lack of satisfactory therapeutic agents; therefore, complementary therapies are required to improve itching symptoms. In the Republic of Korea, Sopoongsan, an herbal formula, has been used to treat itching, dizziness, and skin paralysis.

Rapid Identification of Paeoniae Radix and Moutan Radicis Cortex Using a SCAR Marker-Based Conventional PCR Assay.

Paeoniae Radix is a herbal medicine prepared from the dried roots of , subsp. , and . Although the herbal medicines prepared from these species are morphologically similar, they have different pharmacological effects depending on how they are processed.

Protective effects of an aqueous extract of larvae against radiation-induced testicular injury in mice.

The larvae of have been used as a food ingredient and are known for their nutritional value and anti-inflammatory properties. However, whether larvae demonstrate protective effects against radiation-induced testicular injury has not been investigated. In this study, the protective effects of an aqueous extract of larvae (PBE) against radiation-induced testicular injury were tested.

Preclinical activities of Linn against aging-related diseases.

Globally, an aging population is increasing, and aging is a natural physiological process and a major risk factor for all age-related diseases. It seriously threatens personal health and imposes a great economic burden. Therefore, there is a growing scientific interest in strategies for well-aging with prevention and treatment of age-related diseases.

Diversity dynamics of microfossils from the Cretaceous to the Neogene show mixed responses to events.

Microfossils have a ubiquitous and well-studied fossil record with temporally and spatially fluctuating diversity, but how this arises and how major events affect speciation and extinction is uncertain. We present one of the first applications of PyRate to a micropalaeontological global occurrence dataset, reconstructing diversification rates within a Bayesian framework from the Mesozoic to the Neogene in four microfossil groups: planktic foraminiferans, calcareous nannofossils, radiolarians and diatoms. Calcareous and siliceous groups demonstrate opposed but inconsistent responses in diversification.

Dietary niche partitioning in Early Jurassic ichthyosaurs from Strawberry Bank.

Jurassic ichthyosaurs dominated upper trophic levels of marine ecosystems. Many species coexisted alongside each another, and it is uncertain whether they competed for the same array of food or divided dietary resources, each specializing in different kinds of prey. Here, we test whether feeding differences existed between species, applying finite element analysis to ichthyosaurs for the first time.

Large size in aquatic tetrapods compensates for high drag caused by extreme body proportions.

Various Mesozoic marine reptile lineages evolved streamlined bodies and efficient lift-based swimming, as seen in modern aquatic mammals. Ichthyosaurs had low-drag bodies, akin to modern dolphins, but plesiosaurs were strikingly different, with long hydrofoil-like limbs and greatly variable neck and trunk proportions. Using computational fluid dynamics, we explore the effect of this extreme morphological variation.

An injured pachypleurosaur (Diapsida: Sauropterygia) from the Middle Triassic Luoping Biota indicating predation pressure in the Mesozoic.

The Middle Triassic Luoping Biota in south-west China represents the inception of modern marine ecosystems, with abundant and diverse arthropods, fishes and marine reptiles, indicating recovery from the Permian-Triassic mass extinction. Here we report a new specimen of the predatory marine reptile Diandongosaurus, based on a nearly complete skeleton. The specimen is larger than most other known pachypleurosaurs, and the body shape, caniniform teeth, clavicle with anterior process, and flat distal end of the anterior caudal ribs show its affinities with Diandongosaurus acutidentatus, while the new specimen is approximately three times larger than the holotype.

Effects of and Extracts in a Rat Model of Osteoarthritis.

The implementation of the Nagoya Protocol highlighted the importance of identifying alternative herbal products that are as effective as traditional medicine. and , two species used in the Korean medicine 'Sok-dan', are used for the treatment of bone- and arthritis-related diseases, and they are often mixed or misused. To identify herbal resources with similar efficacy, we compared the effects of extract (DAE) and extract (PUE) on osteoarthritis (OA) in a monosodium iodoacetate (MIA)-induced OA rat model.

Gekko gecko extract attenuates airway inflammation and mucus hypersecretion in a murine model of ovalbumin-induced asthma.

Ethnopharmacological Relevance: Gekko gecko is used as a traditional medicine for various diseases including respiratory disorders in northeast Asian countries, mainly Korea, Japan, and China.

Aim Of The Study: Allergic asthma is a chronic respiratory disease caused by an inappropriate immune response. Due to the recent spread of coronavirus disease 2019, interest in the treatment of pulmonary disorders has rapidly increased.

Plastid Phylogenomic Data Offers Novel Insights Into the Taxonomic Status of the Complex (Cucurbitaceae) in South Korea.

is a genus in Cucurbitaceae comprising 90-100 species. species are valuable as herbaceous medicinal ingredients. The fruits, seeds, and roots of species such as and are used in Korean traditional herbal medicines.

PCR-based rapid diagnostic tools for the authentication of medicinal mistletoe species.

Background: Taxilli Herba (TH) and Visci Herba (VH), defined as the leaves and branches of the mistletoe species Taxillus chinensis and Viscum coloratum, respectively, are popular herbal medicines in East Asia. However, commercial TH and VH products are frequently adulterated with related inauthentic mistletoe species, posing efficacy and safety concerns. Accurate species identification of herbal medicinal products is a prerequisite for quality control, but traditional morphological identification methods are hampered by difficulties in discriminating among closely related species and in identifying the source materials in processed products.