Fungal quorum sensing molecules as potential drugs in the treatment of chronic wounds and their delivery.

Introduction: Chronic non-healing wounds have emerged as a significant global healthcare challenge. Biofilm induced wound infections has been widely acknowledged. Despite the advanced understanding of biofilm formation, the existing approaches for diagnosing biofilms in wounds remain considerably suboptimal.

Biodegradable polylactic acid emulsion ink based on carbon nanotubes and silver for printed pressure sensors.

Investigating biodegradable and biocompatible materials for electronic applications can lead to tangible outcomes such as developing green-electronic devices and reducing the amount of e-waste. The proposed emulsion-based conducting ink formulation takes into consideration circular economy and green principles throughout the entire process, from the selection of materials to the production process. The ink is formulated using the biopolymer polylactic acid dissolved in a sustainable solvent mixed with water, along with conductive carbon nanotubes (CNTs) and silver flakes as fillers.

Anatomy beyond the pandemic: A Q-methodology study exploring student perceptions toward a hybrid curriculum.

As a result of the COVID-19 pandemic, anatomy education was forced to adopt online modes of delivery. Previous research on student views revealed areas of strong preference (asynchronous lectures) and strong dislike (virtual specimens) in online anatomy courses. The current study seeks to compare the views of a single cohort of students experiencing both online and in-person undergraduate introductory anatomy and physiology courses.

Efficacy of a New Alcohol-Free Organic Acid-Based Hand Sanitizer against Foodborne Pathogens.

In light of the global health crisis triggered by the COVID-19 pandemic, numerous experts have deemed the utilization of hand sanitizers imperative as a precautionary measure against the virus. Consequently, the demand for hand sanitizers has experienced a substantial surge. Since the beginning of 2020, the utilization of alcohol-free hand sanitizers has been increasingly favored due to the potential risks associated with alcohol poisoning, flammability, as well as the adverse effects on skin lipid dissolution, dehydration, and sebum reduction, which can lead to severe cases of eczema and norovirus infections.

Ciprofloxacin-Loaded Polyvinylpyrrolidone Foils for the Topical Treatment of Wound Infections with Methicillin-Resistant (MRSA).

Bacterial infections are a constant challenge in the management of acute and chronic wounds. Chronic wounds, such as diabetic foot ulcers, have increased significantly in the last few years due to the rise of an aging population. A better understanding of the infectious pathophysiological mechanisms is urgently needed along with new options for the treatment of wound infections and wound-healing disorders.

Automated grading of anatomical objective structured practical examinations using decision trees: An artificial intelligence approach.

An Objective Structured Practical Examination (OSPE) is an effective and robust, but resource-intensive, means of evaluating anatomical knowledge. Since most OSPEs employ short answer or fill-in-the-blank style questions, the format requires many people familiar with the content to mark the examinations. However, the increasing prevalence of online delivery for anatomy and physiology courses could result in students losing the OSPE practice that they would receive in face-to-face learning sessions.

A longitudinal Q-study to assess changes in students' perceptions at the time of pandemic.

The COVID-19 pandemic forced many universities and colleges to rapidly adopt online course delivery. As with any new foray, realizing the optimal aspects of a course to change became incredibly important for course instructors. In this study, we used a particularly sensitive method, i.

Controlled Drug Release from Nanoengineered Polysaccharides.

Polysaccharides are naturally occurring complex molecules with exceptional physicochemical properties and bioactivities. They originate from plant, animal, and microbial-based resources and processes and can be chemically modified. The biocompatibility and biodegradability of polysaccharides enable their increased use in nanoscale synthesis and engineering for drug encapsulation and release.

Experimental Evaluation of New Geopolymer Composite with Inclusion of Slag and Construction Waste Firebrick at Elevated Temperatures.

This study investigates the effect of elevated temperatures on slag-based geopolymer composites (SGC) with the inclusion of firebrick powder (FBP). There is a limited understanding of the properties of SGC with the inclusion of FBP when exposed to elevated temperatures and the effects of cooling processes in air and water. In this regard, in the preliminary trials performed, optimum molarity, curing temperature, and curing time conditions were determined as 16 molarity, 100 °C, and 24 h, respectively, for SGCs.

Health in Our Hands: diabetes and substance use education through a new genomic framework for schools and communities.

From May 2014 through June 2019, educational, health, and academic partners under an NIH Science Education Partnership Award (SEPA) engaged 1271 6th through 8th grade students and their families in the "A New Genomic Framework for Schools and Communities" program. Evaluation addressed the effectiveness of the Health in Our Hands genomics curriculum, which employed Next Generation Science Standards and community action research projects to target two common, complex conditions-type 2 diabetes and substance use disorder (SUD)-in the underserved cities of Flint and Detroit, MI, USA. Curriculum outcomes were measured with classroom surveys, presentation event questionnaires, and adult interviews using mixed qualitative/quantitative (SPSS V.

MEMS-Based Tactile Sensors: Materials, Processes and Applications in Robotics.

Commonly encountered problems in the manipulation of objects with robotic hands are the contact force control and the setting of approaching motion. Microelectromechanical systems (MEMS) sensors on robots offer several solutions to these problems along with new capabilities. In this review, we analyze tactile, force and/or pressure sensors produced by MEMS technologies including off-the-shelf products such as MEMS barometric sensors.

Occupational therapists' application of the Do-Live-Well framework: A Canadian health promotion approach.

The Do-Live-Well (DLW) framework is an occupation-focused health promotion approach. Online and in-person DLW educational workshops were offered to encourage occupational therapists to apply the DLW concepts. The purpose of this study was to understand workshop participants' experiences of and perspectives on using the DLW framework to support its application in the future.

Digital Transformation of Faculty Development: Responding and Supporting Academia During Disruptions Caused by the Coronavirus Disease 2019 Pandemic.

Introduction: The coronavirus disease 2019 pandemic disrupted the current practices for teaching and learning in medical and health professions education, creating challenges and opportunities for rapid transition. The authors describe how McMaster University's Program for Faculty Development (MacPFD) responded to this disruption by engaging in a digital transformation.

Methods: The digital transformation process of MacPFD was mapped to the conceptual framework of digital transformation: Vial's building blocks of the framework.

Advances in Fibrin-Based Materials in Wound Repair: A Review.

The first bioprocess that occurs in response to wounding is the deterrence of local hemorrhage. This is accomplished by platelet aggregation and initiation of the hemostasis cascade. The resulting blood clot immediately enables the cessation of bleeding and then functions as a provisional matrix for wound healing, which begins a few days after injury.

Biodegradable, Stretchable and Transparent Plastic Films from Modified Waterborne Polyurethane Dispersions.

Waterborne polyurethane dispersions can be designed to generate highly functional and environmentally friendly polymer systems. The use of water as the main dispersion medium is very advantageous for the environment and the introduction of linear and aliphatic polyols such as polyether and polyesters in the formulations can make them highly biocompatible and susceptible to biodegradation. In this study, we fabricated biodegradable, flexible and transparent plastic films by hybridizing a waterborne aliphatic polyester polyurethane (PU) suspension with polyvinylpyrrolidone (PVP) using mechanical homogenization in water.

Comparing Web-Based and In-Person Educational Workshops for Canadian Occupational Therapists and Understanding Their Learning Experiences: Mixed Methods Study.

Background: The Do-Live-Well (DLW) framework is an occupation-focused health promotion approach. Occupational therapists (OTs) have been interested in training opportunities regarding this framework. Traditionally, in-person continuing educational interventions are the main way that OTs obtain knowledge, but web-based learning has become popular among health care professionals.

Recent Advances in Antioxidant Polymers: From Sustainable and Natural Monomers to Synthesis and Applications.

Advances in technology have led to the production of sustainable antioxidants and natural monomers for food packaging and targeted drug delivery applications. Of particular importance is the synthesis of lignin polymers, and graft polymers, dopamine, and polydopamine, inulin, quercetin, limonene, and vitamins, due to their free radical scavenging ability, chemical potency, ideal functional groups for polymerization, abundance in the natural environment, ease of production, and activation of biological mechanisms such as the inhibition of the cellular activation of various signaling pathways, including NF-κB and MAPK. The radical oxygen species are responsible for oxidative damage and increased susceptibility to cancer, cardiovascular, degenerative musculoskeletal, and neurodegenerative conditions and diabetes; such biological mechanisms are inhibited by both synthetic and naturally occurring antioxidants.

4D printing: Perspectives for the production of sustainable plastics for agriculture.

The concept of 4D printing of phase change materials is gaining attention in the potential development of self-healing materials for tissue engineering and manufacturing applications, but there has been limited utilization of the technology in agriculture/farm-based applications. The temperature-responsiveness, magneto-responsiveness, pH-responsiveness, and osmotic pressure-responsiveness of shape-memory materials have potential applications in green/compostable plastics for agricultural applications such as food packaging and mulching films, shade nets, and greenhouse polymer covers. The application of 4D printing in augmenting the biodegradability, environmental, economic, and production benefits of polymers in agriculture is the main focus of this review.

Visual outcome after rhegmatogenous retinal detachment repair surgery in patients with multifocal vs monofocal intraocular lenses.

Purpose: To evaluate functional outcome after retinal detachment (RD) repair surgery in eyes with a multifocal intraocular lens (mIOL).

Setting: Ludwig-Maximilians-University, Munich, Germany.

Design: Single-center case control study.

UV-Blocking, Transparent, and Antioxidant Polycyanoacrylate Films.

Applications of cyanoacrylate monomers are generally limited to adhesives/glues (instant or superglues) and forensic sciences. They tend to polymerize rapidly into rigid structures when exposed to trace amounts of moisture. Transforming cyanoacrylate monomers into transparent polymeric films or coatings can open up several new applications, as they are biocompatible, biodegradable and have surgical uses.

Bioresin-based superhydrophobic coatings with reduced bacterial adhesion.

Hypothesis: Certain biobased polymers or natural compounds can be effectively used in superhydrophobic coating formulations to reduce environmental impact of fluorinated compounds and related bioaccumulation and toxicity problems. Many environmental concerns have thus far been raised in relation to toxicity of solvents and C8 fluorine chemicals. Elimination of these important elements from non-wettable coating formulations can jeopardize non-wetting performance significantly.