Impact of the SARS-CoV-2 pandemic on ophthalmic care in Germany.

Background: Survey by the commission for cross-sectoral ophthalmology, as a joint commission of the German Ophthalmological Society (DOG) and the Professional Association of German Ophthalmologists (BVA) on the effects of the SARS-CoV‑2 pandemic on ophthalmological patient care in Germany.

Methods: Online-based survey.

Results: A total of 1190 questionnaires were (partly) answered.

[Impacts of the SARS-CoV-2 pandemic on ophthalmic care in Germany].

Background: Survey by the commission for cross-sectoral ophthalmology, as a joint commission of the German Ophthalmological Society (DOG) and the Professional Association of German Ophthalmologists (BVA) on the effects of the SARS-CoV‑2 pandemic on ophthalmological patient care in Germany.

Methods: Online-based survey.

Results: A total of 1190 questionnaires were (partly) answered.

[Advertising or information in ophthalmology? : Scientific evaluation of a YouTube sample].

Background: Despite the liberalization of the Therapeutic Products Advertising Act, advertising that praises, misleads or compares is still contrary to the German professional conduct. In view of the increasing commitment of financial investors and the economization in ophthalmology, this study was initiated to examine and check which (advertising) statements are affected in openly accessible videos on the YouTube platform.

Methods: Using the search terms "ophthalmologist" and "eye center" as well as predefined criteria (German origin, audio track with spoken text, duration >1 min), videos were identified and transcribed into an anonymized text version.

A two-axis goniometer for low-temperature nuclear magnetic resonance measurements on single crystals.

We report on the construction of a two-axis goniometer intended for low-temperature, single-crystal nuclear magnetic resonance (NMR) measurements. With the use of home-made and commercially available parts, our simple probe-head design achieves good sensitivity, while maintaining a high angular precision and the ability to orient samples also when cooled to liquid helium temperatures. The probe with the goniometer is adapted to be inserted into a commercial (4)He-flow cryostat, which fits into a wide-bore superconducting solenoid magnet.

Long-term improvement of metabolic control by acarbose in type 2 diabetes patients poorly controlled with maximum sulfonylurea therapy.

Background And Objective: Multiple oral therapies are required long term for the majority of patients with type 2 diabetes mellitus to achieve acceptable glycaemic levels; alternatively, insulin therapy has to be initiated. This study investigated the addition of acarbose to maximum doses of sulfonylurea in very poorly controlled type 2 diabetes patients and assessed its effect in delaying further glycaemic deterioration.

Study Design: In this 78-week, double-blind, placebo-controlled European study, patients were randomised to receive acarbose, titrated to a maximum dose of 100mg three times daily, or matching placebo.

Delay of type I diabetes in high risk, first degree relatives by parenteral antigen administration: the Schwabing Insulin Prophylaxis Pilot Trial.

The Schwabing Insulin Prophylaxis Trial is a randomised, controlled pilot study designed to examine whether insulin therapy can delay or prevent the clinical onset of Type I diabetes in high risk first degree relatives of people with the disease. First degree relatives of patients with Type I diabetes, who were aged 4 years or more, had an islet cell antibody (ICA) value more than 20 Juvenile Diabetes Foundation Units (JDF-U), a reduced first phase insulin response (FPI) to an i.v.

ACE-inhibition with perindopril in essential hypertensive patients with concomitant diseases. The Perindopril Therapeutic Safety Collaborative Research Group.

Purpose: Many hypertensive patients have other, usually long-term diseases. Antihypertensive therapy may interfere with these diseases and their therapies. In the present study, the possible interactions of the ACE-inhibitor perindopril with several of the most common long-term diseases was evaluated.

Silicone replica technique and automatic confocal topometry for determination of corneal surface roughness.

No method for the objective measurement of corneal surface roughness has thus far been available for experimental and clinical investigations. The surface roughness of photoablated porcine corneas was investigated with the silicone-cast method and automatic confocal topometry. Photoablation was performed with the 193-nm excimer laser.

[Silicone impression procedure. Principles for determining ablation and healing parameters in vitro and in vivo].

Topometry and measurement of photoablation patterns are key questions for keratorefractive photoablation. So far, ablation rates have been determined either by tissue perforation or histological micrometry. A cast of irradiated cornea was made by using a 2-component silicon that polymerizes within minutes, thus preserving the corneal topography immediately after photoablation.

[Combination therapy of oral antidiabetic drugs with insulin].

The treatment of type II diabetes should not only concentrate on blood glucose levels but also should take symptoms like insulin resistance, hyperinsulinemia, low HDL-cholesterol, high VLDL, and systemic hypertension into consideration. These symptoms are well described by the metabolic syndrome and are known to be risk factors of macroangiopathy. In obese type II diabetic patients weight loss by caloric restriction is the most essential therapeutic step.

[A new method for diagnostic-therapeutic evaluation of rhinomanometry results].

We have developed a new method for the clinical evaluation of nasal permeability by comparing flow (Vt) and subjectively estimated patency (D). In a coordinate system Vt is marked on the y-axis and D is recorded on the x-axis. The y-axis is separated into an operative and a non-operative part.

Silicon cast method for quantification of photoablation.

Background: Topometry and measurement of photoablation patterns are key questions for keratorefractive photoablation. Ablation rates have been determined previously by either tissue perforation or by micrometry performed on histologic sections.

Methods: A three-dimensional cast of cornea after irradiation was made by using a two-component silicon gel that polymerizes within minutes, thus preserving the corneal topography immediately after photoablation.

[Intraocular availability of liposome encapsulated monoclonal antibodies in the rabbit model. Results of a pilot study].

The results of local application of monoclonal antibodies (mAb) in rabbit eyes are presented. To improve intraocular access of the high-molecular-weight protein it was entrapped in large (0.2 microns) unilamellar, negatively charged liposomes.

[The structure of the morbidity among people working at computers with video display terminals].

The authors analyzed data of ane examination of 407 user of video display terminals of large computer centers in Kiev and revealed high morbidity of the circulatory digestive and locomotor organs. An analysis of 878 analogous cases in the GDR revealed lower involvement of the mentioned organs. Causes are analyzed.

[Laser-induced occlusion of corneal blood vessels with variable emission and absorption].

Laser light has repeatedly been proposed for the occlusion of corneal neovascularizations. Priority has to be given to minimize laser energy in order to limit side effects such as corneal burns. We investigate the influence of variable emission wavelength using a dye laser or dye-enhanced absorption with intravenous sodium fluorescein.