Publications by authors named "B-K Na"
Background: This study was designed to compare diagnostic categories of thyroid fine needle aspiration cytology (FNAC) and incidence of thyroid tumors in the multi-institutional Asian series with a special focus on diagnostic category IV (suspicious for a follicular neoplasm) and follicular thyroid carcinomas (FTCs).
Methods: Distribution of FNAC categories, incidence of thyroid tumors in resection specimens and cytologic diagnoses of surgically confirmed follicular adenomas (FAs) and FTCs were collected from 10 institutes from five Asian countries and were compared among countries and between FAs and FTCs.
Results: The frequency of category IV diagnoses (3.
Prognostic Value of Pulmonary Artery Systolic Pressure in Severe Rheumatic Mitral Stenosis.
Circ Cardiovasc Imaging
October 2024
Background: Current guidelines recommend intervention for asymptomatic rheumatic mitral stenosis (MS) with mitral valve area ≤1.5 cm based on indicators including pulmonary arterial systolic pressure (PASP) >50 mm Hg and new-onset atrial fibrillation; however, evidence supporting this is lacking.
Methods: This single-center retrospective study included patients with rheumatic MS between 2006 and 2022.
Article Synopsis
- The study examined how fluctuations in blood sugar levels (glycemic variability) relate to brain health markers, such as white matter hyperintensities and beta-amyloid plaques, as well as cognitive decline.
- Results indicated that higher glycemic variability was linked to a greater presence of severe white matter changes and increased beta-amyloid accumulation.
- Additionally, these brain changes partially influenced the relationship between glycemic variability and cognitive functions like memory and executive function.
Objective: To investigate the association between genotype and β-amyloid (Aβ) burden, as measured by PET in patients with subcortical vascular cognitive impairment (SVCI) and those with Alzheimer disease-related cognitive impairment (ADCI).
Methods: This was a cross-sectional study of 310 patients with SVCI and 999 with ADCI. To evaluate the effects of genotype or diagnostic group on Aβ positivity, we performed multivariate logistic regression analyses.
Mice harboring the human R138X loss-of-function mutation have increased insulin secretory capacity.
Proc Natl Acad Sci U S A
August 2018
encodes a zinc transporter that is primarily expressed in the pancreatic islets of Langerhans. In β-cells it transports zinc into insulin-containing secretory granules. Loss-of-function (LOF) mutations in protect against type 2 diabetes in humans.
View Article and Find Full Text PDFBackground: Recent evidence suggests that the diagnostic accuracy of myocardial perfusion imaging is improved by quantifying stress myocardial blood flow (MBF) in absolute terms. We evaluated a comprehensive quantitative (13)N-ammonia positron emission tomography ((13)NH3-PET) diagnostic panel, including stress MBF, coronary flow reserve (CFR), and relative flow reserve (RFR) in conjunction with relative perfusion defect (PD) assessments to better detect functionally significant coronary artery stenosis.
Methods And Results: A total of 130 patients (307 vessels) with coronary artery disease underwent both (13)NH3-PET and invasive coronary angiography with fractional flow reserve (FFR) measurement.