Publications by authors named "B de Bruyne"

Background: In the era of first-generation drug-eluting stents and angiography-guided percutaneous coronary intervention (PCI), the presence of a bifurcation lesion was associated with adverse outcomes after PCI. In contrast, the presence of a bifurcation lesion had no impact on outcomes following coronary artery bypass grafting (CABG). Therefore, the presence of a coronary bifurcation lesion requires special attention when choosing between CABG and PCI.

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Article Synopsis
  • The study examines gender differences in the relationship between angiographic findings and fractional flow reserve (FFR) in patients with coronary stenosis.
  • Median FFR values were found to be higher in female patients than in male patients, and a 50% diameter stenosis (DS) is identified as the best threshold for detecting ischemic FFR in both genders.
  • While a higher DS threshold (≥ 59%) improves lesion classification in females, it also results in a higher rate of false negatives.
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Background: Outcomes in women after fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) using current-generation drug-eluting stents (DES) compared with coronary artery bypass grafting (CABG) are unknown.

Objectives: This study sought to evaluate differences in clinical outcomes according to sex after FFR-guided PCI with current generation DES compared with CABG.

Methods: The FAME 3 trial was an investigator-initiated, randomized controlled trial, comparing FFR-guided PCI with current generation DES or CABG in patients with 3-vessel coronary artery disease.

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Article Synopsis
  • Robotic-assisted coronary interventions (R-PCI) have shown safety and effectiveness in treating various coronary lesions, but their real-world clinical outcomes remain unclear.
  • A study evaluated 111 patients to assess major adverse cardiovascular events (MACE) and found a low occurrence of 5.4% during a median follow-up period.
  • The research indicated that while procedural complexity increased time and radiation exposure, it did not impact in-hospital or long-term outcomes, and CCTA-guided procedures allowed for a higher rate of same-day discharge (64.6% vs. 44.2%).
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