Publications by authors named "B de Bie"

Migraine is one of the most common neurological disorders in the US. Currently, the diagnosis and management of migraine are based primarily on subjective self-reported measures, which compromises the reliability of clinical diagnosis and the ability to robustly discern candidacy for available therapies and track treatment response. In this study, we used a computational pipeline for the automated, rapid, high-throughput, and objective analysis of encephalography (EEG) data at Cleveland Clinic to identify signatures that correlate with migraine.

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Article Synopsis
  • Dystrobrevin beta (DTNB) is part of the dystrophin-associated protein complex and its expression is influenced by the long noncoding RNA (lncRNA) HOXD-AS1, particularly in hepatocellular carcinoma (HCC) cells.
  • High levels of DTNB in HCC are linked to various clinical factors like tumor stage and prognosis, indicating its role as an independent risk marker for patient survival.
  • Investigations suggest DTNB regulates the cell cycle and is involved in immune responses and drug sensitivity in HCC, with a potential regulatory mechanism involving a ceRNA network with HOXD-AS1 and miR-139-3p.
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Currently, the optimal treatment to increase the chance of pregnancy and live birth in patients with colorectal endometriosis and subfertility is unknown. Evidence suggests that that both surgery and in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) are effective in improving live birth rate (LBR) among these women. However, the available evidence is of low quality, reports highly heterogeneous results, lacks direct comparison between both treatment options and does not assess whether a combination strategy results in a higher LBR compared to IVF/ICSI-only treatment.

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Objectives: To observe the correlation between growth impairment induced by long-term oral glucocorticoids (GC) therapy and the ratio of FGF23/Klotho in children with primary nephrotic syndrome (PNS).

Methods: A prospective study was conducted on 56 children with GC-sensitive PNS who had discontinued GC therapy for more than 3 months and revisited the Department of Pediatrics of the First Affiliated Hospital of Henan University of Traditional Chinese Medicine between June 2022 and December 2022. After monitoring qualitative and quantitative urine protein levels upon admission, the children with proteinuria relapse were treated with GC (GC group; =29), while those without relapse did not receive GC treatment (non-GC group; =27).

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