Publications by authors named "B Zibrat"
Hemorrhagic fever with renal syndrome (HFRS) is an acute zoonotic disease caused by viruses of the genus. This syndrome is characterized by renal and cardiopulmonary implications detectable with different biomarkers. Here, we explored the role of serum and urine levels of lipocalin-2, endothelin-1 and N-terminal pro-brain natriuretic peptide (NT-proBNP) in HFRS pathology.
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- Arboviruses transmitted by mosquitoes contribute to millions of deaths annually, while recent discoveries have identified many insect-specific viruses (ISVs) in these mosquitoes that cannot infect vertebrates.
- This study focused on Agua Salud alphavirus (ASALV), an insect-specific alphavirus, and its interaction with the mosquito's RNA interference (RNAi) antiviral response, revealing that the knockdown of certain RNAi proteins enhances ASALV replication.
- The findings suggest that ASALV's interaction with the RNAi mechanism in mosquitoes has distinct differences from other arthropod-borne alphaviruses, indicating a need for further research on ISVs and their antiviral strategies.
The global spread of invasive mosquito species increases arbovirus infections. In addition to the invasive species and has spread within Central Europe. Extensive information on its vector competence is missing.
View Article and Find Full Text PDFAn outbreak of haemorrhagic fever with renal syndrome (HFRS) started on Medvednica mountain near Zagreb in January 2012. In order to detect the aetiological agent of the disease in small rodents and to make the link with the human outbreak, rodents were trapped at four different altitudes. Using nested RT-PCR, Puumala virus (PUUV) RNA was detected in 41/53 (77·4%) bank voles (Myodes glareolus) and Dobrava virus (DOBV) RNA was found in 6/61 (9·8%) yellow-necked mice (Apodemus flavicollis).
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