Publications by authors named "B Yehuda"
Background: The American Academy of Pediatrics advises that the nutrition of preterm infants should target a body composition similar to that of a fetus in utero. Still, reference charts for intrauterine body composition are missing. Moreover, data on sexual differences in intrauterine body composition during pregnancy are limited.
View Article and Find Full Text PDFPlacental-related fetal growth restriction, resulting from placental dysfunction, impacts 3-5% of pregnancies and is linked to elevated risk of adverse neurodevelopmental outcomes. In response, the fetus employs a mechanism known as brain-sparing, redirecting blood flow to the cerebral circuit, for adequate supply to the brain. In this study we aimed to quantitatively evaluate disparities in gyrification and brain volumes among fetal growth restriction, small for gestational age and appropriate-for gestational-age fetuses.
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- The study aims to develop an automated method to quantitatively assess fetal brain gyrification using standard 2D MR imaging, instead of relying on subjective visual assessments.
- It involves analyzing imaging data of 162 fetuses—134 controls and 28 with lissencephaly or polymicrogyria—to calculate various gyrification parameters and differentiate between normal and abnormal conditions.
- Results indicate significant changes in gyrification with gestational age for normal fetuses, as well as reductions in lissencephaly and polymicrogyria cases, with machine learning algorithms effectively classifying these conditions.
Background: Small for gestational age (SGA) fetuses are at risk for perinatal adverse outcomes. Fetal body composition reflects the fetal nutrition status and hold promise as potential prognostic indicator. MRI quantification of fetal anthropometrics may enhance SGA risk stratification.
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- Researchers studied how electrical activity affects the structure of neurons, specifically looking at the cytoskeleton, which gives neurons their shape.
- They used high-resolution electron microscopy to observe changes in the sciatic nerve of mice after applying different frequencies of electric pulses.
- The results showed that neuronal stimulation significantly reduced the density of key cytoskeletal proteins, suggesting that this chemical change may help facilitate neuronal function and shape in response to electrical signals.