Publications by authors named "B Yalcin"
Favipiravir, a broad-spectrum RNA-dependent RNA polymerase inhibitor widely used during the COVID-19 pandemic, effectively reduces viral load but has been linked to inflammatory changes in tissues such as the liver and kidneys. High-dose and prolonged use of favipiravir for COVID-19 raises concerns about its potential toxic effects on the lungs, particularly in patients with pre-existing pulmonary conditions. This study investigated favipiravir's effects on lung tissue in healthy rats.
View Article and Find Full Text PDFObjective: Childhood cancer treatment disrupts vaccination schedules and weakens or eliminates vaccine-induced immunity. In addition, post-treatment vaccine responses vary. This study aimed to assess post-treatment serum antibody levels and vaccine responses in children.
View Article and Find Full Text PDFObjective: Methotrexate (MTX) is a highly effective chemotherapy for cancer. This drug has a gonadotoxic effect, mainly in the testes and ovaries. Our study used histopathological and immunohistochemical methods to assess the potential damage to testicular and ovarian tissue caused by MTX use.
View Article and Find Full Text PDFArticle Synopsis
- Endometrium cancer is the most common gynecological cancer in developed countries, and this study was conducted to assess how HER2 positivity affects patient prognosis.
- The study analyzed 121 patients diagnosed with endometrial cancer between September 2019 and December 2023, categorizing them into HER2-low and HER2-high groups based on their HER2 immunohistochemistry scores.
- Findings showed that those in the HER2-high group had better survival outcomes than those in the HER2-low group, and both FIGO stage and HER2 status emerged as independent risk factors influencing overall survival.