Publications by authors named "B Y Jamoh"
The clinical severity of sickle cell disease (SCD) is strongly influenced by the level of fetal haemoglobin (HbF) persistent in each patient. Three major HbF loci (BCL11A, HBS1L-MYB, and Xmn1-HBG2) have been reported, but a considerable hidden heritability remains. We conducted a genome-wide association study for HbF levels in 1006 Nigerian patients with SCD (HbSS/HbSβ0), followed by a replication and meta-analysis exercise in four independent SCD cohorts (3,582 patients).
View Article and Find Full Text PDFBackground: An estimated 75% of Nigerians are at risk of hepatitis B virus (HBV) exposure. In an attempt to reduce the menace, the assessment of risk factors associated with HBV infection and general perception of infected individuals is a step in that direction.
Aim Of The Study: This study, therefore, identified exposure to risk factors and general perceptions associated with HBV infection in infected individuals in Zaria, Nigeria.
Hepatitis B virus (HBV) is one of the major causes of morbidity and mortality worldwide. The aim of this study was to determine the haematological and immunological parameters in patients with chronic HBV infection in Zaria, Nigeria. Twenty individuals with confirmed chronic HBV (CHB) infection constituted the subjects while 20 non-HBV-infected individuals were monitored as controls.
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- Hepatitis B virus (HBV) is highly prevalent in Nigeria, with genotype E being the most common strain found in Zaria.
- A study analyzed blood samples from 165 participants to identify the HBV genotypes, revealing that 83.6% had detectable HBV DNA, mostly in mixed genotypes.
- The findings showed five HBV genotypes, with HBV/E (97.1%) as the most frequent, followed by HBV/B (82.6%), and lower rates for HBV/A, C, and D, highlighting the mixed nature of infections in the region.
Complement Levels in Nigeria Patients with Sickle Cell Anaemia in the Asymptomatic State.
Niger J Clin Pract
September 2018
Objectives: Significantly low serum levels of complement components have been reported in patients with Sickle cell anaemia (SCA) which may result in a high susceptibility to infections. However some studies have reported a normal or high complement level. The aim of our study was to assess some haematological parameters and Complement levels in adult patients with steady state SCA in Zaria, North western Nigeria.
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