Genomic Investigation and Comparative Analysis of European High-Risk Clone of ST2.

Multidrug-resistant is a major concern in healthcare institutions worldwide. Several reports described the dissemination of high-risk clones that are responsible for a high number of difficult-to-treat infections. In our study, 19 multidrug-resistant strains from Budapest, Hungary, were investigated based on whole-genome sequencing (WGS).

Tracing carriage, acquisition, and transmission of ESBL-producing Escherichia coli over two years in a tertiary care hospital.

Background: The impact of community carriage on the influx of extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-E) into hospitals remains understudied. In this prospective 2-year single-centre study, we investigate the community ESBL-E influx and trace the colonisation, nosocomial acquisition, transmission, and infection dynamics of ESBL-producing Escherichia coli (ESBL-Ec) in non-ICU wards at a tertiary care hospital.

Methods: This study reports primary and post hoc outcomes of the clinical trial NCT01208519 in which hospitalised patients were screened for rectal carriage of ESBL-E.

A new tool to quantify biodiversity change under landscape transformation.

Identifying how species richness or diversity changes with different proportions of natural and anthropized environments in the landscape is important for landscape management for conservation. Here, we propose a new method to assess biodiversity changes in landscapes with varying proportions of habitat types. The algorithm is based on the resampling of individuals recorded in different habitats considering both the proportion occupied by each habitat in the landscape and the number of individuals recorded in each habitat.