Publications by authors named "B Wolfrum"
Two-dimensional layered materials (2DLMs) have received increasing attention for their potential in bioelectronics due to their favorable electrical, optical, and mechanical properties. The transformation of the planar structures of 2DLMs into complex 3D shapes is a key strategic step toward creating conformal biointerfaces with cells and applying them as scaffolds to simultaneously guide their growth to tissues and enable integrated bioelectronic monitoring. Using a strain-engineered self-foldable bilayer, we demonstrate the facile formation of predetermined 3D microstructures of 2DLMs with controllable curvatures, called microrolls.
View Article and Find Full Text PDFThe successful development of a metal-organic framework (MOF)-derived Co/CoO/C core-shell composite integrated into laser-induced graphitic (LIG) carbon electrodes for electrochemical sensing is reported. The sensors are fabricated via a direct laser scribing technique using a UV laser (355 nm wavelength) to induce the photothermolysis of rationally selected ZIF-67 into the LIG matrix. Electrochemical characterization reveals that the incorporation of the laser-scribed ZIF-67-derived composite on the electrode surface reduces the impedance more than 100 times compared with bare LIG sensors.
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- A novel type of superabsorbent hydrogels was created by cross-linking hydrophilic poly(vinylphosphonates) through a process called photochemical reaction, which involves light to trigger the bonding.
- The process included synthesizing specific copolymers using a rare earth metal technique, followed by modifications to introduce vinylphosphonic acid, leading to significant water absorption capabilities of up to 150g of water per g of hydrogel.
- The hydrogels were shown to respond to changes in pH, with experiments demonstrating their ability to swell and deswell reversibly in response to acidic or basic environments, making them suitable for use as sensors in various applications.
The rapid and reliable detection and quantification of nucleic acids is crucial for various applications, including infectious disease and cancer diagnostics. While conventional methods, such as the quantitative polymerase chain reaction are widely used, they are limited to the laboratory environment due to their complexity and the requirement for sophisticated equipment. In this study, we present a novel amplification-free digital sensing strategy by combining the collateral cleavage activity of the Cas12a enzyme with single-impact electrochemistry.
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