Background: Long noncoding RNAs (lncRNAs) play a critical role in gastric cancer (GC) progression and metastasis. However, research comprehensively exploring tissue-derived lncRNAs for predicting peritoneal recurrence in patients with GC remains limited. This study aims to investigate the transcriptional landscape of lncRNAs in GC with peritoneal metastasis (PM) and to develop an integrated lncRNA-based score to predict peritoneal recurrence in patients with GC after radical gastrectomy.
View Article and Find Full Text PDFPurposes: The objective of this study was to investigate intra-articular distal radius fractures, aiming to provide a comprehensive analysis of fracture patterns and discuss the corresponding treatment strategies for each pattern.
Methods: 294 cases of intra-articular distal radius fractures lines were collected and clustered thorough K-means and hierarchical clustering algorithm. The demographic data of patients and the clinical treatment outcomes were recorded.
It is becoming increasingly evident that diabetic vascular complications seriously threaten human health. The most prevalent microvascular complications include kidney disease, retinal disease, cardiovascular diseases and amputation. Conventional treatments can only relieve the progression of the diseases, and is no longer appropriate for the long-term management of diabetic patients.
View Article and Find Full Text PDFOptimizing an emergency air pollution control strategy for haze events presents a significant challenge due to the extensive computational demands required to quantify the complex nonlinearity associated with controls on diverse air pollutants and regional sources. In this study, we developed a forecasting tool for emergency air pollution control strategies based on a predictive response surface model that quantifies PM responses to emission changes from different pollutants and regions. This tool is equipped to assess the effectiveness of emergency control measures corresponding to various air pollution alerts and to formulate an optimized control strategy aimed at specific PM targets.
View Article and Find Full Text PDFBackground: Uncertainty in illness is regarded as a source of stress, and tends to have adverse consequences on quality of life among older adults with chronic heart failure (CHF).
Objective: The purpose of this study was to identify distinct subgroups in uncertainty in illness, and to explore associated factors within the population of older adults with CHF.
Methods: We conducted a cross-sectional study using convenience sampling to survey 311 hospitalized older adults with CHF.