Publications by authors named "B W Russ"

The neurotransmitter dopamine (DA) has a multifaceted role in healthy and disordered brains through its action on multiple subtypes of dopaminergic receptors. How modulation of these receptors influences learning and motivation by altering intrinsic brain-wide networks remains unclear. Here we performed parallel behavioral and resting-state functional MRI experiments after administration of two different DA receptor antagonists in male and female macaque monkeys.

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One of the most significant and surprising recent developments in nanocrystal studies was the observation of superfluorescence from a system of self-assembled, colloidal perovskite nanocrystals [G. Rainò, M. A.

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Flexibly adjusting our behavioral strategies based on the environmental context is critical to maximize rewards. Ventrolateral prefrontal cortex (vlPFC) has been implicated in both learning and decision-making for probabilistic rewards, although how context influences these processes remains unclear. We collected functional neuroimaging data while rhesus macaques performed a probabilistic learning task in two contexts: one with novel and another with familiar visual stimuli.

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Article Synopsis
  • Corticostriatal connections play a key role in motivation and behavior, and rs-fMRI is being explored as a tool to investigate these connections in relation to neuropsychiatric disorders.
  • The study used tract-tracing in non-human primates to confirm that rs-fMRI data reflects these connections in both primates and humans, mapping the striatal input from various prefrontal regions.
  • They found significant overlap in striatal projection zones, particularly in the medial rostral dorsal caudate, providing a foundation for future research that could lead to targeted treatments for neurological and psychiatric conditions.
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Article Synopsis
  • Recent research has created normative growth charts for the brain structure of rhesus macaques, filling a gap in understanding nonhuman primate neurodevelopment.
  • The study analyzed 1,522 MRI scans from 1,024 macaques to identify developmental patterns in brain volume, cortical thickness, and surface area throughout their lifespan.
  • These findings not only highlight key milestones in macaque brain development but also allow for meaningful comparisons to human brain maturation, providing a valuable resource for future neuroscience studies.
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