Chronic Sinonasal Inflammation as a Comorbidity of Respiratory Epithelial Adenomatoid Hamartoma: A 15-Year Retrospective Observational Study.

Respiratory epithelial adenomatoid hamartoma (REAH) is a benign pseudo-glandular proliferation of the nasal cavity with poorly-understood etiopathogenesis. This study aimed to examine the frequency of comorbidities in patients with REAH and to determine whether comorbidity affects the clinical characteristics of REAH. A retrospective cohort study included patients with REAH treated at 2 university hospitals over 15 years.

Middle Turbinate Vascular Malformation Associated With Angiofibroma Originating From the Nasal Septum: A Case Report.

According to the latest classification of vascular lesions, cavernous hemangioma is considered a venous or arteriovenous malformation. The literature has not described the association between vascular malformation of the middle turbinate and angiofibroma of the nasal septum. A 26-year-old female patient with profuse left-sided bleeding and nasal obstruction is presented.

Impact of and gene polymorphisms on prognosis and survival of patients with oral squamous cell carcinoma.

Despite significant efforts in developing new diagnostic and therapeutic modalities, oral squamous cell carcinomas (OSCCs) still exhibit a high recurrence rate, a low five-year survival rate, and an increasing prevalence. Toll-like receptors (TLRs), which initiate and perpetuate immune mechanisms upon activation, have been linked to immune surveillance and the antitumor immune response. The aim of this study was to investigate the association between the polymorphisms of the TLR7 rs3853839 and TLR9 rs187084 genes and OSCC risk, clinicopathological features, and survival.

Angiogenesis and eosinophilia in the nasal mucosa of patients with different clinical phenotypes of chronic rhinosinusitis.

Introduction: Dense inflammatory cell infiltration and vascularization of the nasal mucosa are histological characteristics of chronic rhinosinusitis (CRS). We aimed to evaluate the association between eosinophilia and vascularization in the stroma of mucosal layer/nasal polyps (NP) and clinical parameters in patients with different phenotypes of CRS.

Methodology: This cross-sectional study involved 33 patients who had CRS with NP without aspirin sensitivity (CRSwNP), 20 NP patients as a part of aspirin-exacerbated respiratory disease (AERD), and 10 patients who had CRS without NP (CRSsNP), selected for surgery.