Publications by authors named "B Virgolici"
Obesity causes fat accumulation, and sarcopenia causes loss of muscle mass and strength; together, they worsen insulin resistance and accelerate muscle decline, creating a harmful cycle. Some supplements, along with physical exercise, could be remedies for sarcopenic obesity (SO). In this review, we aim to draw a comparison between supplements studied in experimental research and those evaluated in clinical studies for SO.
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- Gamma-glutamyltransferase (GGT) is a liver enzyme that indicates inflammation and oxidative stress, and its levels are elevated in type 2 diabetes, particularly in patients with dysglycaemia and dyslipidemia.
- The study involved 85 type 2 diabetes patients aged 40-70 years, divided into subgroups based on GGT levels, revealing that those with high GGT exhibited higher inflammatory markers and signs of endothelial dysfunction.
- The findings suggest that in non-alcoholic diabetic patients with less than 6 years of diabetes, elevated GGT levels, along with markers like sICAM, serum MCP-1, and TNF-α, may signal significant metabolic issues.
EFFECTS OF OMEGA-3 FATTY ACIDS ASSOCIATED WITH ANTIOXIDANT VITAMINS IN OVERWEIGHT AND OBESE CHILDREN.
Acta Endocrinol (Buchar)
October 2023
Introduction: Antioxidants and unsaturated fatty acids have protective effects in obesity.
Aim: We investigated the benefits of Omega-3 fatty acids associated with antioxidant vitamins in obese children. Magnesemia and calcemia were observed in relation with other metabolic parameters, before and after the treatment.
HEMATOLOGICAL INDICES RELATED TO VITAMIN D DEFICIENCY IN OBESE CHILDREN.
Acta Endocrinol (Buchar)
January 2022
Introduction: Vitamin D is involved in differentiation and induction of erythropoiesis in bone marrow cells.
Aim: We compared the serum 25(OH) vitamin D level in obese children control and found correlations between vitamin D level and hematological indices in obese children.
Materials And Methods: 25 overweight and obese patients and 15 normal weight children were enrolled in an observational study .
MATERNAL-FETAL METABOLISM DISORDERS INDUCED BY MATERNAL OBESITY IN AN ANIMAL MODEL.
Acta Endocrinol (Buchar)
January 2016
Context: Adipokines secreted by fat cells are vital to the control of energy metabolism, communicating the nutrient status with the tissues responsible for controlling both energy intake and expenditure and insulin sensitivity.
Objective: We aimed to prove in an experimental animal study that maternal obesity has long term adverse fetal metabolic consequences, which pass on even to the next generation of descendants.
Design: The effects of maternal obesity have been studied on animal model using 50 obese female Wistar rats, in which we induced obesity by high-calorie high-fat diet administered by gavage.