Publications by authors named "B Vincent Crist"

More than 70 million adults in the United States are impacted by osteoarthritis (OA). Symptomatic articular cartilage loss that progresses to debilitating OA is being diagnosed more frequently and earlier in life, such that a growing number of active patients are faced with life-altering healthcare decisions at increasingly younger ages. Joint replacement surgeries, in the form of various artificial arthroplasties, are reliable operations, especially for older (>65 years), more sedentary patients with end-stage OA, but have major limitations for younger, more active patients.

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Objectives: To delineate the key factors associated with treatment success or failure for patients undergoing lower extremity osteotomies to address a spectrum of lower extremity joint and limb deformities at an Integrated Limb Preservation Center (ILPC).

Methods: Retrospective cohort study. Level I Academic Trauma Center.

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Background: Osteochondral allograft (OCA) transplantation with or without labral reconstruction is considered a hip preservation surgical treatment option for young, active patients. This study aims to report early outcomes for use of OCA and labrum allograft transplants for patients treated for symptomatic femoral head chondral damage and/or acetabular labrum deficiency after implementation of a comprehensive joint restoration approach.

Methods: 33 patients from a lifelong registry were included for analysis.

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Article Synopsis
  • Osteochondral allograft transplantation (OCAT) is a promising treatment for joint defects but has high failure rates due to poor osteochondral allograft (OCA) osseointegration.
  • This study tests the local delivery of deferoxamine (DFO), an iron chelator that promotes bone healing, to enhance OCA osseointegration in canine models of OCAT in the knee and hip.
  • Results showed that DFO-treated sites had better joint function, increased bone volume, and improved new bone growth compared to control sites, suggesting it may help reduce failure rates in joint restoration.
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Introduction During the COVID-19 pandemic, the AO Foundation, an orthopedic education organization, had to transition its live education programs to an online format. Skills that were previously evaluated and corrected in person by educators were now assessed through online lectures and discussion groups. Our goal was to evaluate an online course designed to teach the skill of "leg length and coronal deformity measurement" and to assess participants' ability to demonstrate this skill using online software.

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