Publications by authors named "B Vandendorpe"
Purpose: To evaluate the oncological outcome after stereotactic body radiation therapy (SBRT) for oligoprogressive metastatic castration-resistant prostate cancer (omCRPC) patients.
Materials-methods: In this retrospective, observational, multi-institutional study, omCRPC patients (≤5 metastases) underwent SBRT. Primary endpoint was systemic therapy escalation-free survival (STE-FS) after SBRT.
Article Synopsis
- The study aimed to assess the outcomes of stereotactic body radiation therapy (SBRT) in patients with oligometastatic hormone-sensitive prostate cancer (omHSPC), focusing on systemic therapy escalation-free survival (STE-FS) and other relapse types.
- Out of 119 patients treated with SBRT, the median STE-FS was 33.4 months, with a local control rate of 95%, though progression events occurred in 60.5% of the patients.
- The findings suggest that SBRT offers good local control with minimal severe side effects, making it a promising option for delaying the start of more intense systemic treatments, but more research is needed for better patient selection and longer-term
Background: The choice between different diffusion-weighted imaging (DWI) techniques is difficult as each comes with tradeoffs for efficient clinical routine imaging and apparent diffusion coefficient (ADC) accuracy.
Purpose: To quantify signal-to-noise-ratio (SNR) efficiency, ADC accuracy, artifacts, and distortions for different DWI acquisition techniques, coils, and scanners.
Study Type: Phantom, in vivo intraindividual biomarker accuracy between DWI techniques and independent ratings.
Background: Management of local recurrence of prostate cancer (PCa) in the prostatic bed after radical prostatectomy (RP) and radiotherapy remains challenging.
Objective: To assess the efficacy and safety of salvage stereotactic body radiotherapy (SBRT) reirradiation in this setting and evaluate prognostic factors.
Design, Setting, And Participants: We conducted a large multicenter retrospective series that included 117 patients who were treated with salvage SBRT for local recurrence in the prostatic bed after RP and radiotherapy in 11 centers across three countries.