Publications by authors named "B Vaidya"
Background: Tenecteplase has been approved for acute ischemic stroke at a dose of 0.2 mg/kg by the Indian licensing authority. A registry to evaluate the safety of tenecteplase was mandated by the licensing authority.
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- This study explored the adverse events (AEs) related to COVID-19 vaccination in patients with rheumatoid arthritis (RA) as part of the COVAD-2 study, which surveyed participants from February to June 2022.
- It included 7203 participants, including 1423 RA patients, and found that RA patients reported higher rates of both major and minor AEs compared to healthy controls, and even more when compared to those with other autoimmune diseases.
- Active RA significantly increased the risk of major AEs and hospitalization, while patients on certain medications like methotrexate or TNF inhibitors experienced fewer AEs than those not on these treatments.
Background: The nature of aberrant salience in schizophrenia, whether it is a state or a trait phenomenon, remains unclear.
Aim: To assess and compare aberrant salience in patients with schizophrenia at different stages of the illness and to explore its association with symptom severity and medication use.
Methods: A total of 113 subjects were included, comprising 83 patients with schizophrenia divided into three groups: group A (acute drug-free symptomatic stage, n = 23), group B (chronic-medicated symptomatic stage, n = 30), and group C (chronic-medicated asymptomatic stage, n = 30).
Children between the ages of one and 18 are at a heightened risk of death and impairment due to traumatic brain injury (TBI). TBI can be deadly and is usually categorized as mild, moderate, or severe according to the Glasgow Coma Scale (GCS). For individuals with a TBI and an abnormal GCS, the preferred modality is non-contrast CT of the head.
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- The study investigates how comorbidities impact the quality of life in patients with idiopathic inflammatory myopathies (IIMs) compared to other autoimmune diseases and healthy individuals, utilizing self-reported data from the COVAD-2 survey.
- Results show IIM patients have significantly higher rates of comorbidities, basic multitasking, complex multitasking, and mental health disorders.
- The presence of these conditions correlates with lower overall physical and mental health scores, suggesting the need for targeted management strategies for IIM patients based on identified clinical clusters.