Publications by authors named "B V Watts"

Objective: Mental health care is delivered by teams that include social workers, psychologists, nonphysician prescribing clinicians (NPPCs), and physicians. The objective of this study was to determine whether patient rurality has an effect on the types of U.S.

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Article Synopsis
  • - The research focuses on developing small-molecule inhibitors (SMIs) targeting the CD40-CD40L interaction to improve islet transplantation outcomes and prevent type 1 diabetes (T1D) in mice.
  • - Promising SMIs DRI-C21041 and DRI-C21095 demonstrated the ability to prolong islet allograft survival and functionality while reducing T1D incidence in NOD mice during trials.
  • - These findings suggest that CD40L-targeting SMIs could provide a safer and more effective alternative to traditional antibody treatments, offering better control and ease of administration for transplant recipients and autoimmune disease prevention.
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Objective: The aim of the study is to characterize geographic variation in electroconvulsive therapy (ECT) receipt across the United States (US) Veterans Administration (VA) healthcare system and explore potential explanatory variables.

Background: ECT is a highly effective and rapidly acting treatment for multiple mental disorders. However, there may be geographic disparities in access to ECT across the US.

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Although cancer cachexia is classically characterized as a systemic inflammatory disorder, emerging evidence indicates that weight loss also associates with local tissue inflammation. We queried the regulation of this inflammation and its causality to cachexia by exploring skeletal muscle, whose atrophy strongly associates with poor outcomes. Using multiple mouse models and patient samples, we show that cachectic muscle is marked by enhanced innate immunity.

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