Publications by authors named "B V Rogachev"

Article Synopsis
  • The study investigates the role of sodium-glucose co-transporter (SGLT) inhibitors in improving ultrafiltration during peritoneal dialysis by reducing glucose absorption from dialysis fluids.
  • Experiments on mice and rats with kidney failure showed that SGLTs are involved in glucose diffusion from the dialysate into the bloodstream, but specific SGLT2 inhibitors did not effectively reduce fluid absorption in the rodent model.
  • The findings suggest that targeting non-SGLT2 pathways may offer a new approach to enhance ultrafiltration and address complications from high blood glucose levels in peritoneal dialysis patients.
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Background: The outcome of patients with chronic kidney disease (CKD) and acute kidney injury (AKI) is often dismal and measures to ameliorate their course are scarce. When admitted to the hospital, kidney patients are often hospitalized in general Medicine wards rather than in a specialized Nephrology department. In the current study, we compared the outcome of two cohorts of kidney patients (CKD and AKI) admitted either to general open-staff (with rotating physicians) Medicine wards or to a closed-staff (non-rotating Nephrologists) Nephrology ward.

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Female patient, suffering from nephrolithiasis, at the age of 32 was admitted for renal colic caused by a stone obstructing UP junction with left hydronephrosis. Nephrostomy was placed, resulting in brisk diuresis. Severe metabolic acidosis with normal anion gap and urine pH of 6.

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Background: Predicting the mortality risk of patients un-dergoing hemodialysis (HD) is challenging. Cell-free DNA (cfDNA) is released into circulation from dying cells, and its elevation is predictive of unfavorable outcome. In a pilot study, we found post-HD cfDNA level to be a predictor of all-cause mortality.

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A patient with extremely high calcium level of 23.9 mg/dL (5.97 mmol/L) was admitted to our department unconscious with pathological ECG recording, demonstrating shortening of QT interval.

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