Antibody Responses in SARS-CoV-2-Exposed and/or Vaccinated Individuals Target Conserved Epitopes from Multiple CoV-2 Antigens.

There is a need to investigate novel strategies in order to create an effective, broadly protective vaccine for current and future severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreaks. The currently available vaccines demonstrate compromised efficacy against emerging SARS-CoV-2 variants of concern (VOCs), short-lived immunity, and susceptibility to immune imprinting due to frequent boosting practices. In this study, we examined the specificity of cross-reactive IgG antibody responses in mRNA-vaccinated, AstraZeneca-vaccinated, and unvaccinated donors to identify potentially conserved, cross-reactive epitopes to target in order to create a broadly protective SARS-CoV-2 vaccine.

High temperature setup for measurement of Hall coefficient and electrical conductivity of thermoelectric materials.

An experimental setup has been developed for the simultaneous measurement of the Hall coefficient (RH) and electrical conductivity (σ) of thermoelectric (TE) specimens in the temperature range of 300-700 K. The van der Pauw geometry is utilized for the RH and σ measurements. The sample holder geometry has been designed for diverse TE specimen dimensions and easy sample mounting.

Effect of beverages, denture cleanser and chlorhexidine gluconate on surface roughness of flexible denture base material: an in vitro study.

Purpose: The purpose of the study was to evaluate and compare the effect of beverages, denture cleanser and chlorhexidine gluconate solution on surface roughness of flexible denture base material.

Materials And Methods: Fifty flexible denture base resin specimens measuring 50±1mm in diameter and 0.5±0.

'Constriction Band Syndrome': Retained Rubber Band as a Less-Known Cause of Pain and Non-healing Sinus Tracts of Wrist in a Paediatric Patient.

Rubber band constriction syndrome has been described in the literature, although there are very few case reports. Non-healing recurrent tenosynovitis and synovitis of the wrist joint demonstrating a circular rubber band on imaging has not been described before. Imaging studies showed retained circular band deep to the extensor tendons, embedded within the joint capsule.