Publications by authors named "B U Wei-Quan"
Article Synopsis
- Pudilan Xiaoyan Oral Liquid is used for treating inflammatory diseases like upper respiratory infections, but the quality can vary due to differences in the active ingredients in Taraxaci Herba, its main ingredient.* -
- A study utilized a Thermo Scientific Vanquish UPLC system to create fingerprints for Taraxaci Herba from different origins, identifying 13 common peaks and noting high similarity in samples (above 0.90) across 29 batches.* -
- The research found significant variations in the content of certain active compounds in Taraxaci Herba from different regions, helping enhance quality control and ensure better quality for Pudilan Xiaoyan Oral Liquid.*
[Identification of quality markers for Pudilan Xiaoyan Oral Liquid].
Zhongguo Zhong Yao Za Zhi
September 2020
On the basis of anti-inflammatory activity, combined with multiple indicators, the quality markers of Pudilan Xiaoyan Oral Liquid were screened and determined for quality control. Lipopolysaccharide(LPS) was used to induce normal human bronchial epithelial cell(NHBE) inflammation model. The anti-inflammatory effects of the main chemical components in Pudilan Xiaoyan Oral Liquid were examined one by one, and the pharmacodynamic basis for the overall anti-inflammatory efficacy of Pudilan Xiaoyan Oral Liquid was clarified to identify the quality markers of Pudilan Xiaoyan Oral Liquid and the contents of the quality markers were determined by high performance liquid chromatography(HPLC).
View Article and Find Full Text PDF[Investigation of active components and mechanism of Pudilan Xiaoyan Oral Liquid based on network pharmacology].
Zhongguo Zhong Yao Za Zhi
September 2020
Article Synopsis
- The study utilizes network pharmacology to explore the active components and mechanisms of Pudilan Xiaoyan Oral Liquid by analyzing its potential targets and interactions.
- It identified 41 active ingredients, including various alkaloids, organic acids, flavonoids, and a coumarin, and established links to diseases like parotitis, tonsillitis, and pharyngitis with specific inflammatory pathways.
- The findings aim to clarify the pharmacodynamic basis and key mechanisms of action of Pudilan Xiaoyan Oral Liquid, potentially aiding in clinical research and promoting its use.