A pharmacist-led intervention to improve kidney transplant recipient outcomes and identify patients at risk of highly variable trough tacrolimus levels: a cohort study.

Objectives: Given the positive impact of appropriate medication management on graft outcome and therefore of patient survival and graft function, the pharmacist's role in the kidney transplantation team has evolved over recent decades. The primary objective of this study was to determine whether pharmacist-led intervention after kidney transplantation is associated with a lower graft rejection rate and intra-patient variation in tacrolimus trough concentrations (C). The study's secondary objective was to develop a questionnaire to identify patients at risk for highly variable C.

Preparation and Physicochemical Stability of Liquid Oral Dosage Forms Free of Potentially Harmful Excipient Designed for Pediatric Patients.

Dexamethasone, hydrochlorothiazide, spironolactone, and phenytoin are commonly used in neonates, but no age-appropriate formulation containing these active pharmaceutical ingredients (APIs) is commercially available. Thus, pharmaceutical compounding of the liquid oral dosage form is required to enable newborn administration. A problem common to the compounded preparations described in the literature is that they include potentially harmful excipients (PHEs).

[Rehabilitation outcomes following knee arthroplasty: a retrospective study of 90 patients].

The objective of rehabilitation after arthroplasty is the restoration of satisfactory joint amplitude and muscular strength. The objective of this study was to determine the reasons for hospitalization for rehabilitation after knee arthroplasty, duration of stay and perioperative morbidity. The retrospective and descriptive study included 90 patients.