Publications by authors named "B Trimarco"
Article Synopsis
- - AHA introduced the term cardiovascular-kidney-metabolic (CKM) syndrome to explain how heart, kidney, and metabolic health conditions interact.
- - A study compared the prevalence of CKM syndrome components before (2017-2019) and during (2020-2022) the COVID-19 pandemic using data from over 81,000 primary care patients.
- - Results showed a significant increase in type 2 diabetes, hypertension, dyslipidemia, obesity, and a 170% rise in prediabetes during the pandemic, with older age groups showing a higher prevalence of CKM conditions.
Introduction: Delay in arterial hypertension (AH) diagnosis and late therapy initiation may affect progression towards hypertensive-mediated organ damage (HMOD) and blood pressure (BP) control.
Aim: We aimed to assess the impact of time-to-therapy on BP control and HMOD in patients receiving AH diagnosis.
Methods: We analysed data from the Campania Salute Network, a prospective registry of hypertensive patients (NCT02211365).
PCSK9 Inhibitors: Is the Time Ripe for the "Fast Track" Use Independently on the LDL-C Baseline Values in Acute Coronary Syndrome?
High Blood Press Cardiovasc Prev
November 2024
The low-density lipoprotein cholesterol (LDL-C) lowering decreases the risk to develop major adverse cardiovascular events (MACE) in patients with acute coronary syndrome (ACS). Therefore, the "fast track" use of PCSK9 inhibitors (PCSK9i) has been introduced in ACS patients not achieving LDL-C target (70 mg/dl) despite an ongoing lipid lowering therapy with statin at maximum tolerated dosage plus ezetimibe or stain-naïve (LDL-C > 130 mg/dl). PCSK9i "fast track" use has shown to achieve the regression of "non-culprit" atherosclerotic plaques leading to a further MACE decrease.
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- Women generally have a lower risk of cardiovascular disease compared to men, but it's unclear how hypertension-related organ damage affects this difference.
- A study assessed whether carotid plaque influences the risk of cardiovascular events in young patients with treated hypertension, finding that women without carotid plaque had a significantly lower risk than men.
- However, when carotid plaque was present, the cardiovascular risk for women was similar to that of men, indicating that carotid plaque neutralizes the protective effect in women.
Article Synopsis
- A 6-year study in Naples, Italy, involving over 228,000 individuals, aimed to analyze the impact of COVID-19 on dyslipidemia incidence, using data from both before and during the pandemic.
- Findings showed a 29% increased risk of dyslipidemia during the pandemic compared to pre-COVID-19, suggesting the need for targeted monitoring for those who've recovered from COVID-19.