Publications by authors named "B Tomberli"
Article Synopsis
- Intracoronary in-stent restenosis (ISR) often happens 3 to 6 months after stent placement; while drug-eluting stents have reduced ISR, cases still occur.
- An 81-year-old woman with a history of multiple heart procedures experienced reiterant ISR, leading researchers to focus on intra-stent factors after excluding others.
- A diagnosis of potential coronary vasculitis was proposed, possibly triggered by the stent, and the patient's ISR did not recur after starting steroid treatment, highlighting the importance of considering biological causes for effective management.
Article Synopsis
- - This study assessed if sodium-glucose cotransporter-2 inhibitors (SGLT2-i) can protect against contrast-induced acute kidney injury (CI-AKI) in heart failure patients undergoing procedures using iodinated contrast.
- - Researchers divided participants into those using SGLT2-i and those not, measuring the occurrence of CI-AKI, overall mortality, and the need for renal therapy during hospitalization.
- - Results showed lower CI-AKI rates in SGLT2-i users (9.3%) compared to non-users (27.3%), and the SGLT2-i group had no need for continuous renal replacement therapy, suggesting that SGLT2-i therapy offers a protective benefit in this context. *
Article Synopsis
- - The study aimed to evaluate the long-term clinical course and mortality outcomes of patients with hypertrophic cardiomyopathy (HCM), building on previous research that typically covered shorter follow-up periods of less than 10 years.
- - A total of 202 patients were monitored over an average of 27 years, revealing that about 52% died during follow-up, with nearly half of those deaths linked to HCM, primarily from heart failure and strokes.
- - Results showed that while HCM-related mortality was relatively low at 1.3% per year, it increased over time, particularly due to heart failure and strokes, and many early deaths occurred before effective treatments were available.
Article Synopsis
- The study investigates how the timing of diagnosis in wild-type transthyretin cardiac amyloidosis (ATTRwt-CA) affects patient outcomes, specifically mortality.
- The research involved reviewing records of 160 patients, revealing that a longer time to diagnosis (median 4 months) correlated with higher mortality rates, especially in those diagnosed after 6 months.
- Findings suggest that earlier diagnosis is crucial, emphasizing the need to recognize symptoms promptly to improve survival chances.