Publications by authors named "B Timothy Baxter"
Hyperglycemia Inhibits AAA Expansion: Examining the Role of Lysyl Oxidase.
Am J Physiol Heart Circ Physiol
December 2024
Abdominal aortic aneurysm (AAA) is a common, progressive and potentially fatal dilation of the most distal aortic segment. Multiple studies with longitudinal follow-up of AAA have identified markedly slower progression among patients affected with diabetes. Understanding the molecular pathway responsible for the growth inhibition could have implications for therapy in nondiabetic AAA patients.
View Article and Find Full Text PDFThe isolation and crystalline structure of ,'-di-benzyl-ethyl-enedi-ammonium dichloride, CHN ·2Cl, is reported. This was obtained as an unintended product of an attempted Curtius rearrangement that involved benzyl-amine as one of the reagents and 1,2-di-chloro-ethane as the solvent. Part of a series of reactions of a course-based undergraduate research experience (CURE), this was not the intended reaction outcome.
View Article and Find Full Text PDFArticle Synopsis
- HSV-1 primarily infects the oral and nasal areas before establishing latency in the trigeminal ganglion and can also infect the central nervous system (CNS) via specific pathways.
- Recent studies have highlighted the lack of detailed knowledge about which brain regions are affected during HSV-1 infections and how microglial responses differ across these regions.
- This study on a mouse model revealed a two-step spread of HSV-1 from the olfactory epithelium to select brain regions, along with varying activation levels of microglia, contributing to understanding HSV-1's role in neurological diseases.
The natural system at Great Salt Lake, Utah, USA was augmented by the construction of a rock-filled railroad causeway in 1960, creating two lakes at one site. The north arm is sequestered from the mountain snowmelt inputs and thus became saturated with salts (250-340 g/L). The south arm is a flourishing ecosystem with moderate salinity (90-190 g/L) and a significant body of water for ten million birds on the avian flyways of the western US who engorge themselves on the large biomass of brine flies and shrimp.
View Article and Find Full Text PDFBackground And Purpose: Intraarterial thrombolysis as an adjunct to mechanical thrombectomy is increasingly being considered to enhance reperfusion in acute ischemic stroke patients. Intraarterial thrombolysis may increase the risk of post-thrombectomy intracerebral hemorrhage (ICH) in certain patient subgroups.
Methods: We analyzed acute ischemic stroke patients treated with mechanical thrombectomy in a multicenter registry.