[Hypothalamic-pituitary-adrenal and hypothalamic-pituitary-thyroid axis findings in depressive disorder].

Objective: To find out whether the neuroendocrine abnormalities, that may be seen in major depressive disorder (MDD), differ during depression and remission periods, compared with the controls.

Method: Twenty subjects, diagnosed as MDD according to DSM -IV, ICD-10, and 20 healthy controls were randomly selected and included in this study. Dexamethasone Suppression Test (DST) and Thyroid Releasing Hormone (TRH) test were performed and basal hormone levels were determined in all subjects.

Different neuroendocrine profiles of remitted and nonremitted schizophrenic patients.

Background: Thyrotropin-releasing hormone (TRH) test and Dexamethasone Suppression Test (DST) are two neuroendocrine tests that have been extensively used in an attempt to predict treatment response and outcome in schizophrenia. The objectives of this study were to investigate (1) the relationship between TRH test and DST and various psychiatric symptoms and (2) the potential value of these tests in prediction of short-term outcome in schizophrenic patients.

Methods: TRH test and DST were administered to 58 patients with schizophrenia.

Blood levels of leukotrienes (LTC4, D4, E4, B4) and synthesis of leukotriene B4 by peripheral leukocytes in children with acute A and B hepatitis.

Leukotrienes (LTs) are cell-membrane derived lipid inflammatory mediators, synthesized and eliminated by the liver. LTs have effects on liver cells in some pathological conditions. In this study, we measured plasma endogenous and liberated leukotriene (LT) concentration in peripheral blood leukocytes stimulated in vitro by the calcium ionophore (CaA23187) and platelet-activating factor (PAF).

Increased gastric juice leukotriene B4, C4 and E4 concentrations in children with Helicobacter pylori colonization.

During recent years, the role of inflammatory lipid mediators in the pathophysiology of Helicobacter pylori (H. pylori) infections has been investigated in several studies. The concentrations of leukotrienes (LTs) in gastric juice from H.