Publications by authors named "B Tamrazi"
Three distinct MN1::BEND2 fusion-positive tumors in pediatric patients. (A) Clinical course for each patient was variable in part due to differences in initial diagnosis. Each patient responded favorably to gross total resection and is stable at last follow-up.
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- The study aimed to assess nnU-Net-based segmentation models for accurately identifying medulloblastoma tumors in pediatric patients using multi-institutional MRI scans.
- It involved 78 patients aged 2 to 18 years and utilized various MRI protocols collected from three hospitals over 19 years, with tumor annotations prepared by expert neuroradiologists.
- Results showed that both transfer learning and direct nnU-Net models achieved decent Dice scores for tumor segmentation, indicating their effectiveness and robustness across different clinical sites.
Pineal parenchymal tumors are rare neoplasms for which evidence-based treatment recommendations are lacking. These tumors vary in biology, clinical characteristics, and prognosis, requiring treatment that ranges from surgical resection alone to intensive multimodal antineoplastic therapy. Recently, international collaborative studies have shed light on the genomic landscape of these tumors, leading to refinement in molecular-based disease classification in the 5th edition of the World Health Organization (WHO) classification of tumors of the central nervous system.
View Article and Find Full Text PDFBackground: Children with neuromuscular early onset scoliosis (EOS) receive numerous radiographic studies both from orthopaedic and other specialties. Ionizing radiation doses delivered by computed tomography (CT) are reportedly 100 times higher than conventional radiography. The purpose of this study was to evaluate the number of radiographic studies ordered for neuromuscular EOS patients during their care.
View Article and Find Full Text PDFBackground: There is no standard treatment for the recurrence of medulloblastoma, the most common malignant childhood brain tumor, and prognosis remains dismal. In this study, we introduce a regimen that is well-tolerated and effective at inducing remission.
Methods: The primary objectives of this study were to assess tolerability of the regimen and overall response rate (ORR).