[Genetic variation at STR-TH01 locus in the South Polish population].

We report on a rare allelic variant of the TH01 STR locus. Within this commonly used tetranucleotide repeat system, we identified and characterized by denaturating gel electrophoresis an allele of the size corresponding to 10.3 repeats, analogous to the most common 9.

Frequency data on the loci vWA, FES/FPS, F13A01, TH01, TPOX and CSF1P0 in a population from South Poland.

Allele and genotype frequencies for six short tandem repeat (STR) loci were determined in a sample of 124 inhabitants from South Poland with commercial PCR-based typing kits. No deviations from Hardy-Weinberg expectations were found. The combined power of discrimination for the six loci was 0.

Data on the loci LDLR, GYPA, HBGG, D7S8 and GC in a south Polish population.

Allele and genotype frequencies were determined in a sample of 102 inhabitants from South Poland with a commercial PCR based typing kit. No deviations from Hardy-Weinberg expectations were found. The combined power of discrimination for the five loci was 0.

D1S80 VNTR locus genotypes in population of south Poland; meta-analysis pointer to genetic disequilibrium of human populations.

A highly variable number of tandem repeats (VNTRs) in a human locus D1S80 can prove to be useful for forensic science purposes. As with other genetic polymorphisms, a database of a local population allelic frequencies is needed to ensure that no departure from genetic equilibrium exists. DNA from the locus D1S80 was amplified by polymerase chain reaction (PCR) and analyzed by horizontal PAGE followed by silver staining.

[Linkage analysis between HLA and GLOI with congenital adrenal hyperplasia due to 21-hydroxylase deficiency].

A linkage analysis was performed between congenital adrenal hyperplasia and HLA-ABC and GLOI loci. On the basis of studies carried out in 23 (HLA) and 20 (GLOI) informative families, linkage between adrenal hyperplasia and locus B of HLA was confirmed, whereas that with GLOI was ruled out.