Trajectory of Cognitive Decline Across Different Racial/Ethnic Groups: The Role of Edentulism.

This study examines whether age-related cognitive decline varies by race/ethnicity and how edentulism moderates these effects. Data from the Health and Retirement Study (2006-2020), including 23,669 respondents aged 51 and above across 189,352 person-wave observations were analyzed. Of all respondents, 13.

Construction of bimetallic oxy-hydroxides based on Ni(OH) nanosheets for sensitive non-enzymatic glucose detection electrochemical oxidation and incorporation.

Due to their ease of synthesis and large specific surface area, Ni(OH) nanosheets have emerged as promising electrochemical sensing materials, attracting significant attention in recent years. Herein, a series of oxy-hydroxides based on Ni(OH) nanosheets, including NiO/Ni(OH)@NF and (MNi)O/Ni(OH)@NF (M = Co, Fe, or Cr), are successfully synthesized the electrochemical oxidation and incorporation strategies. Electrochemical tests demonstrate that these Ni(OH)-based oxy-hydroxides exhibit excellent electrochemical oxidation activity for glucose in alkaline electrolyte.

Engineering Planar Crystallinity in Nitrogen-Vacancy-Incorporated Carbon Nitride for Efficient Photoredox Catalysis.

The concurrent evolution of value-added benzimidazole compounds and hydrogen within the domain of chemical synthesis is of paramount importance. The utilization of photocatalysis enhances both the efficiency and environmental benignity of the synthetic process. However, it is profoundly challenging within a photocatalytic system to simultaneously augment the number of active sites and the internal transport rate of photogenerated charge carriers.

Endoplasmic reticulum stress-MMRN1 positive feedback contributes to cisplatin resistance in small cell lung cancer.

Background: Small cell lung cancer (SCLC) accounts for 15% of all lung cancers and presents early metastasis and poor prognosis. Chemotherapy with cisplatin (CDDP) remains one of the standards of care in first-line treatment. However, the emergence of acquired resistance to CDDP causes disease progression and cancer recurrence.

Acceptor Elongation Boosted Intersystem Crossing Affords Efficient NIR Type-I and AIE-Active Photosensitizers for Targeting Ferroptosis-Based Cancer Therapy.

Photosensitizers (PSs) featuring type I reactive oxygen species (ROS) generation and aggregation-induced emission (AIE) activity offer a promising solution to achieve non-invasive and precise theranostics. However, the reported AIE luminogens (AIEgens) with both AIE characteristic and strong type-I ROS generation are still scarce and the structure-property relationship is still unclear. Herein, an innovative acceptor elongation boosted intersystem crossing (AEBIC) design strategy has been proposed to endow the AIEgen strong type-I ROS producibility.