Expansion of KPC-producing Enterobacterales in four large hospitals in Hanoi, Vietnam.

Objectives: The incidence of carbapenem resistance among nosocomial Gram-negative bacteria in Vietnam is high and increasing, including among Enterobacterales. In this study, we assessed the presence of one of the main carbapenemase genes, bla, among carbapenem-resistant Enterobacterales (CRE) from four large hospitals in Hanoi, Vietnam, between 2010 and 2015, and described their key molecular characteristics.

Methods: KPC-producing Enterobacterales were detected using conventional PCR and were further analysed using S1 nuclease pulsed-field gel electrophoresis (S1-PFGE), Southern blotting and whole-genome sequencing (WGS) for sequence typing and genetic characterisation.

First report of pneumonia and septic shock caused by in Vietnam.

is rarely known to cause infections in humans. We report the first case of pneumonia and septic shock caused by in a 38-year-old man in Vietnam. may be an emerging infectious agent in humans.

First report of biliary tract infection caused by multidrug-resistant .

is widely distributed in nature and a rare human pathogen. We report the first Case of biliary tract infection due to multidrug-resistant in a 78-year-old woman in Vietnam. Bile culture grew .

First report of infective endocarditis caused by in Vietnam.

We report a first case of bacteraemia causing infective endocarditis in a 40-year-old man in Vietnam. This is the second case of infective endocarditis in the literature. The patient was successfully treated by antibiotics, combined with aortic valve replacement.