Publications by authors named "B T Mohammed"
Background: Thrombin prefers substrates carrying Arg at the site of cleavage (P1) because of the presence of D189 in the primary specificity (S1) pocket but can also cleave substrates carrying Phe at P1. The structural basis of this property is unknown.
Objective: Solve the X-ray structure of thrombin bound to a ligand carrying Phe at P1 and investigate the effects of replacing D189.
Background: Thrombin prefers substrates carrying Arg at the site of cleavage (P1) because of the presence of D189 in the primary specificity (S1) pocket but can also cleave substrates carrying Phe at P1. The structural basis of this property is unknown.
Objectives: Solve the X-ray structure of thrombin bound to a ligand carrying Phe at P1 and investigate the effects of replacing D189.
Article Synopsis
- In-utero exposure to Zika virus (ZIKV) can result in severe outcomes like miscarriage and congenital Zika syndrome, prompting a study on the infection rates among pregnant women from February to April 2022.
- Researchers tested 200 pregnant women for ZIKV antibodies and found that 16.5% had ZIKV IgM, 10% had IgG, and 23% had neutralizing antibodies, indicating various stages of infection and immunity.
- The study also revealed that recent ZIKV infections were more common in sexually active women aged 20-29, with higher infection risks in first trimester and grand-multiparous women, although no significant link was found between ZIKV and specific pregnancy trimest
Introduction: Globally, 2.4 million neonates died in their first month of life in 2019 with approximately 6,700 neonatal deaths every day. Ethiopia is 4th among the top 10 countries with the highest number of neonatal deaths.
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- Animal Source Foods (ASFs) include various products like meat, dairy, and eggs, which are crucial for preventing malnutrition, especially among vulnerable groups like adolescents and pregnant women.
- A study conducted in Central Ethiopia revealed that 51.1% of school-aged adolescent girls were not consuming ASFs, and 29% of them had anemia.
- The research found a significant link between not consuming ASFs and the presence of anemia, suggesting that improving ASF intake could be vital for their growth and health.