Asian experience with the Pintucci keratoprosthesis.

Purpose: To report the outcome of a retrospective study of the Pintucci Biointegrable Keratoprosthesis (PBIKP) in Asian eyes.

Materials And Methods: This was a retrospective analysis of 31 eyes of 31 consecutive patients, who underwent surgery with implantation of the PBIKP. The age ranged from 7 years to 65 years, with a mean age of 34 years.

Management of chemical injuries of the eye.

The extreme morbidity that a severe chemical burn produces makes it imperative that immediate treatment be instituted for the purpose of restoration of the integrity and transparency of the cornea. The evolution of cicatrisation in severe chemical injuries especially alkali, takes an unfavourable course. Release of collagenase from the newly formed epithelium and fibroblasts of the stroma and lack of required levels of ascorbate in the aqueous humour causes fibroblasts to develop a denatured weak collagen.

Reproductive endocrine effects of intranasal administration of norethisterone (NET) to women.

Four consecutive menstrual cycles were studied in six healthy parous women. A solvent mixture comprising propylene glycol:ethanol:water (3:3:4) was sprayed intranasally daily using a glass atomizer between days 5 and 24 of the first (control) menstrual cycle. NET was dissolved in the solvent and similarly administered at a daily dose of 100 mcg during the second and third menstrual cycles.