Publications by authors named "B T CHADWICK"

Article Synopsis
  • Cryptococcus neoformans is a soil fungus that causes over 180,000 deaths annually and requires adaptation to carbon monoxide (CO) levels in its host to be virulent.
  • Researchers used genetic mapping techniques on progeny from a CO-tolerant clinical strain and a CO-sensitive environmental strain to identify key genetic regions involved in CO tolerance.
  • The study found that CO tolerance is linked to virulence in mouse models, suggesting that even CO-sensitive strains can adapt to become more virulent in a host environment.
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Anthropogenic stressors like overfishing, land based runoff, and increasing temperatures cause the degradation of coral reefs, leading to the loss of corals and other calcifiers, increases in competitive fleshy algae, and increases in microbial pathogen abundance and hypoxia. To test the hypothesis that corals would be healthier by moving them off the benthos, a common garden experiment was conducted in which corals were translocated to midwater geodesic spheres (hereafter called Coral Reef Arks or Arks). Coral fragments translocated to the Arks survived significantly longer than equivalent coral fragments translocated to Control sites (.

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Objective: To evaluate the impact of inflammation on anticoagulation monitoring for patients supported with extracorporeal membrane oxygenation (ECMO).

Design: Prospective single-center cohort study.

Setting: University-affiliated tertiary care academic medical center.

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Carbon dioxide supplies carbon for photosynthetic species and is a major product of respiration for all life forms. Inside the human body where CO is a by-product of the tricarboxylic acid cycle, its level reaches 5% or higher. In the ambient atmosphere, ∼.

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Unlabelled: causes cryptococcal meningoencephalitis, a disease that kills more than 180,000 people annually. Contributing to its success as a fungal pathogen is its cell wall surrounded by a capsule. When the cryptococcal cell wall is compromised, exposed pathogen-associated molecular pattern molecules (PAMPs) could trigger host recognition and initiate attack against this fungus.

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