Publications by authors named "B T Brans"

Article Synopsis
  • This study investigates the causes of ongoing pain in patients after posterior lumbar interbody fusion (PLIF) surgery by using F-fluoride PET/CT scans and patient-reported outcomes.
  • A total of 36 patients were examined, and those who reported pain had abnormal PET scan results around pedicle screws and facet joints, while CT scans showed no significant differences.
  • The results suggest that PET/CT scans are more effective in correlating with patient symptoms than CT scans alone, highlighting changes in bone metabolism that indicate recovery or potential issues post-surgery.
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We present a rare case of intimal angiosarcoma arising from the iliac artery with unusual symptoms and signs mimicking retroperitoneal fibrosis (RPF). This 84-year-old male presented with constitutional symptoms, abdominal pain, increased acute-phase reactant levels, impaired renal function and a CT-documented left-sided parailiac soft-tissue mass with unilateral extrinsic ureteric obstruction. Whole-body F-fluorodeoxyglucose positron emission tomography scan showed highly increased FDG-uptake in a horseshoe-like pattern surrounding the left common iliac artery, but no pathologic activity elsewhere.

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Positive surgical margins for invasive breast cancer (BC) treated with breast-conserving surgery (BCS) are defined as ink on tumor. The rate of positive margins is approximately 20%, since a time- and cost-effective method for margin assessment is lacking. In this study, we investigated margin status by intra-operative imaging using high-resolution F-fluoro-deoxyglucose (FDG) positron emission tomography (PET) and X-ray computed tomography (CT).

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Introduction: Brown adipose tissue (BAT) is considered as a potential target for combating obesity in humans where active BAT metabolizes glucose and fatty acids as fuel resulting in heat production. Prospective studies in humans have been set up to further study the presence and metabolic activity of BAT mostly using Positron Emission Tomography (PET) imaging in cold-stimulated conditions with the radiolabeled glucose derivative [18F]FDG. However, radiotracers beyond [18F]FDG have been proposed to investigate BAT activity, targeting various aspects of BAT metabolism.

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Prostate-specific membrane antigen (PSMA) is highly overexpressed in prostate cancer. Many PSMA analog radiotracers for PET/CT prostate cancer staging have been developed, such as Ga-PSMA-11. This radiotracer has achieved good results in multiple clinical trials, but because of the superior imaging characteristics of F-fluoride, F-PSMA-11 was developed.

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