[The pharmacoeconomics of testicular cancer in Ukraine].

An ever-growing cost of health care in Ukraine attest to the need for an optimum employment of resources in diagnosing and treating disorders of major public health significance, testicular carcinoma (TC) among their number. The authors consider it expedient to ascertain TC costs and design an analytical framework for the diagnostic and therapeutic options to be assessed properly. The following combination chemotherapy regimens were found to be associated with high response rates and acceptable longterm survival: BEP, PE programmes for primary treatment and PEI programme for recurrent or refractory TC.

[The prevention and treatment of nausea and vomiting during cancer chemotherapy].

From the point of view of patients nausea and vomiting is a very important side effect of chemotherapy. The above events can be successfully controlled with modern antiemetic therapy. Use of high doses of metoclopramide in combination with dexamethasone and lorazepame is one of the routine means of administration of chemotherapeutic treatments with the benefit being derived in 30 to 70% of patients.

[The use of cryopreserved hemopoietic cells of the human embryonic liver in stable depressions of hematopoiesis in cancer patients].

As many as 29 oncological patients with severe depression of hemopoiesis secondary to cytostatic therapy underwent transfusion of fetal liver cells (FLC) from human embryos in the 8-12 weeks stage of their development cryopreserved in 5% DMCO at -196 degrees C as to the method elaborated at the Institute of Problems in Cryobiology and Cryomedicine. A strong correlation was found between infusion of a certain FLC dose and rise in leucocyte counts, which rise occurred by day 13-16 (r = +0.846).