Impact of intraocular pressure regulation on visual fields in open-angle glaucoma.

Objective: To investigate the correlation of different parameters of intraocular pressure (IOP) to visual field decay in open-angle glaucoma.

Design: Analysis of visual field decay during a prospective, randomized clinical trial comparing primary laser trabeculoplasty with medication.

Participants: Of a total of 82 included eyes in 82 patients with newly detected high-pressure open-angle glaucomas, 76 (55 capsular, 21 simple) fulfilled the 2-year follow-up with the stated number of reliable visual field examinations and were included in this analysis.

Primary argon laser trabeculoplasty vs pilocarpine. IV. Long-term effects on optic nerve head.

In a prospective, randomized study on primary argon laser trabeculoplasty vs piloparpine in 82 newly detected open-angle glaucomas the progress of optic nerve head damage is presented. In 70 patients reliable stereo photographs could be analysed. In the laser treated group a progression of glaucoma damage after 24 months was seen in 6/37 eyes (16%) and in the pilocarpine-treated group 16/33 (49%) (p = 0.

Primary argon laser trabeculoplasty vs pilocarpine. III. Long-term effects on visual fields.

In a prospective randomized study on primary argon laser trabeculoplasty vs pilocarpine in 82 newly detected open-angle glaucoma patients, visual field changes were analysed for absolute changes over 2 years on automated threshold perimetry and manual Goldmann perimetry. Regression analysis was also performed using the threshold perimetry examinations taken every second month. Analyses based on automatic perimetry were corrected for eventual bias due to cataract and induced miosis.

Primary argon laser trabeculoplasty vs pilocarpine. II: Long-term effects on intraocular pressure and facility of outflow. Study design and additional therapy.

In a prospective study 82 patients recently diagnosed with simple or capsular glaucoma were randomized to receive primary argon laser trabeculoplasty or pilocarpine treatment. A 2-year follow-up showed a better success rate in the laser group, with less need for additional therapy. The average intraocular pressure and peak pressure was lower and the daytime pressure variation was significantly less in the laser group.

Primary argon laser trabeculoplasty vs. pilocarpine. Short-term effects.

This is a prospective study of 82 newly discovered patients with simplex or capsular glaucoma from two centres, collected between 1984 and 1989 and selected at random for primary treatment by either laser or pilocarpine. Preliminary two-year follow-up shows that primary laser treatment gives a significantly higher number of patients where the intraocular pressure is successfully controlled. Primary argon laser trabeculoplasty has been carried out in 40 patients.